年轻乳腺癌患者:相同还是不同的实体?

Paola Iturralde-Rosas Priego
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引用次数: 1

摘要

乳腺癌是育龄妇女最常见的病理;大约7%的乳腺癌是在40岁以下的妇女中诊断出来的,相当于在这一群体中诊断出的所有恶性疾病的40%以上。遗传因素在年轻患者乳腺癌的发生中起着重要作用。然而,由于其临床用途有限,且必须考虑多种因素,因此分析起来并不容易。我们进行了一项回顾性研究,纳入了2010年1月至2014年7月期间在一家私立医疗中心诊断为乳腺癌的年龄在40岁及以下的女性患者。研究方案包括完整的临床研究,放射学报告,如乳房x线摄影和/或超声图像,组织病理学和免疫组织化学报告。该研究纳入46例患者,平均发病年龄为37.1岁,标准差(SD)为±3.02岁,中位数为38岁。各种变量,如肿瘤特征、危险因素和所提供的治疗,也有不同的百分比。年轻的乳腺癌患者应该由多学科的工作人员单独治疗和评估,因为这种病理实体显示出特定的特征,使得这组患者难以治疗,需要特别注意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Breast Cancer in Young Patients: Same or Different Entity?
Overview Breast cancer is the most common pathology in women of reproductive age; approximately 7% of breast carcinomas are diagnosed in women less than 40 years of age, corresponding to more than 40% of all malignant diseases diagnosed in this group. Genetic factors play a fundamental role in the genesis of the breast cancer in young patients. However, it is not easy to analyze them because their clinical usefulness is limited and there are multiple factors that must be considered. We conducted a retrospective study in which we included female patients of ages 40 years old or less, diagnosed with breast cancer at a private medical center during the period of January 2010 to July 2014. The protocol of the study included a complete clinical study, radiological reports as mammography and/or ultrasound image, histopathological and immunohistochemistry reports. The study included 46 patients with an average age of presentation of 37.1 years, a standard deviation (SD) of ±3.02 years and a median of 38 years. There were also different percentages for the various variables such as tumor characteristics, risk factors, and treatment provided. Young patients with breast cancer should be treated and evaluated individually by a multidisciplinary staff, as this pathological entity shows specific characteristics that makes this group of patients difficult to treat and warrants special considerations.
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