Spectral analysis of DNA sequence using recursive weiner khinchine theorem: a comparative approach

Locating protein coding regions (exons) in Eukaryotes is one of the key problems of gene identification. The period-3 peaks observed in spectra of exons are often used as the landmark indicating existence of coding region in genes. Spectral Analysis by Discrete Fourier Transform (DFT) and filtering are popular methods adopted by various researchers from the field of Digital Signal Processing to accomplish this purpose. Many of the researchers have used Celegan gene as their sample database for exon prediction. Hence authors in this paper have identified F56F11.4a gene of Celegan Chromosome IE as their test database and have applied Recursive Weiner Khinchine Theorem (RWKT) for spectral analysis. On comparison it shows that results obtained by RWKT method gives better spectral resolution and clarity than DFT method.