{"title":"利福平-甲氧苄啶联合反应动力学。","authors":"G Buniva, R Palminteri, M Berti","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Two different regimens of a rifampicin-trimethoprim combination were studied in two groups of healthy volunteers. Each regimen was administered for seven consecutive days. In the first, the treatment consisted of 300 mg of rifampicin and 80 mg of trimethoprim administered t.i.d. In the second 450 mg of rifampicin and 120 mg of trimethoprim were administered b.i.d. Data on serum levels and urinary excretion are discussed.</p>","PeriodicalId":75937,"journal":{"name":"International journal of clinical pharmacology and biopharmacy","volume":"17 6","pages":"256-9"},"PeriodicalIF":0.0000,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Kinetics of a rifampicin-trimethoprim combination.\",\"authors\":\"G Buniva, R Palminteri, M Berti\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Two different regimens of a rifampicin-trimethoprim combination were studied in two groups of healthy volunteers. Each regimen was administered for seven consecutive days. In the first, the treatment consisted of 300 mg of rifampicin and 80 mg of trimethoprim administered t.i.d. In the second 450 mg of rifampicin and 120 mg of trimethoprim were administered b.i.d. Data on serum levels and urinary excretion are discussed.</p>\",\"PeriodicalId\":75937,\"journal\":{\"name\":\"International journal of clinical pharmacology and biopharmacy\",\"volume\":\"17 6\",\"pages\":\"256-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of clinical pharmacology and biopharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of clinical pharmacology and biopharmacy","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Kinetics of a rifampicin-trimethoprim combination.
Two different regimens of a rifampicin-trimethoprim combination were studied in two groups of healthy volunteers. Each regimen was administered for seven consecutive days. In the first, the treatment consisted of 300 mg of rifampicin and 80 mg of trimethoprim administered t.i.d. In the second 450 mg of rifampicin and 120 mg of trimethoprim were administered b.i.d. Data on serum levels and urinary excretion are discussed.