乳腺癌患者血清白蛋白水平:与总生存率的相关性

R. Kaur, Rubal, M. Dhiman, Rajesh Vashitstha, A. Munshi
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引用次数: 5

摘要

白蛋白是指示营养不良和炎症的重要生物标志物。本研究的目的是评估旁遮普马尔瓦地区乳腺癌患者的白蛋白水平及其与总生存率的关系。材料和方法:本研究计划在旁遮普省马尔瓦地区进行。样本来自古鲁·戈宾德·辛格医学院和医院以及马克斯医院。白蛋白水平的估计是在旁遮普中央大学完成的,250名乳腺癌患者和250名年龄和性别匹配的对照组参与了这项研究。使用全自动生物分析仪Erba 200估计白蛋白水平。随访时间间隔为3、6、12和15个月,以确定乳腺癌患者的结果。结果:与对照组相比,在患病人群中发现低水平的白蛋白(p 3.5 g/dl)与乳腺癌患者总生存率的增加显著相关。在据报道乳腺癌发病率很高的旁遮普邦马尔瓦地区,白蛋白估计可能是一种简单而廉价的疾病风险评估和结果评估工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Serum Albumin Levels in BreastCancer: Correlation with OverallSurvival
Introduction: Albumin in an important biomarker that indicates malnutrition as well as inflammation. The aim of the study was to evaluate the albumin levels in breast cancer patients and its association with overall survival among breast cancer patients of Malwa region of Punjab. Material and methods: The study was planned in Malwa region of Punjab. Sampling was done from Guru Gobind Singh Medical College and Hospital and Max Hospital. The estimation of albumin levels was done at Central University of Punjab. 250 patients with breast cancer and 250 age and sex matched controls were involved in the study. Albumin levels were estimated using fully automated bio analyzer Erba 200. Follow-up interviews were conducted at an interval of 3, 6, 12 and 15 months to determine the outcome among breast cancer patients. Results: Low levels of albumin was found among the diseased in comparison with controls (p 3.5 g/dl) are associated significantly with increased overall survival among breast cancer patients. Albumin estimation may be a simple and inexpensive tool for the risk assessment and outcome of the disease in Malwa region of Punjab where the incidence of breast cancer is reported to be very high.
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