基于MEMS的微粒子检测流式细胞仪及其仪器系统在医疗保健中的应用

2018 Recent Advances on Engineering, Technology and Computational Sciences (RAETCS) Pub Date : 2018-02-01 DOI:10.1109/RAETCS.2018.8443893

Mahesh Kumar, Debanjan Das

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引用次数: 3

摘要

生物细胞的检测、计数和分析是医疗保健系统的一个重要方面，微流控阻抗流式细胞仪已被全球广泛接受，用于高速测量微细胞/颗粒的介电参数。允许细胞/颗粒通过具有平面底电极的微通道。通过必要的信号调理电路和数据采集系统，施加直流电压并记录微流控装置的输出。在本工作中，我们分析了直径为10μm的聚苯乙烯颗粒在磷酸盐缓冲盐水介质中流动，其电导率为0.156Sm−1，成功地证明了流式细胞仪的有效性。

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MEMS based Flow Cytometer with Instrumentation System for Detection of Micro Particles for Health Care Applications

Detection, counting and analysis of biological cells is an important aspect in health care systems for which a microfluidic impedance flow cytometers have been globally accepted to measure the dielectric parameters of micro cells/particles at high speed. The cells/particles are allowed through a micro-channel having planar bottom electrodes. DC voltage is applied and output of the microfluidic device is recorded through necessary signal conditioning circuit and data acquisition system. In the present work, polystyrene particles of 10μm diameter flowing in medium of phosphate buffered saline having conductivity of 0.156Sm−1 are analyzed to successfully demonstrate the efficacy of the flow cytometer.

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来源期刊

2018 Recent Advances on Engineering, Technology and Computational Sciences (RAETCS)

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