打印胶囊天线用于药物依从性监测的可行性研究

Hong Yu, G. Flores, S. Reza, G. Irby, C. Batich, R. Bashirullah, V. Meka, D. M. Peterson, N. Euliano
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引用次数: 3

摘要

本文对打印胶囊天线用于药物依从性监测的可行性进行了研究。在临床试验中,确切地了解患者对药物治疗方案的依从性是很重要的,因为没有它,就不能准确地解释结果。直接印在标准胶囊表面的小天线有可能作为一种经济有效的方法,通过电子检测消化道中吞下的药丸来验证药物依从性。在本文中,我们研究了这些“电子药丸”的各个方面,包括印刷方法、导电油墨和人体内电子小天线的辐射特性。我们采用真实的天线模型和基于时域有限差分法的电磁模拟来确定体内源的辐射场强。具有近似等效于生物组织的电学特性的幻影溶液用于实验验证模拟结果并表征人体躯干中电小辐射源的信号衰减。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Feasibility Study of Printed Capsule Antennas for Medication Compliance Monitoring
This paper presents a feasibility study of printed capsule antennas for medication compliance monitoring. During clinical trials, it is important to know with certainty a patient's compliance to a medication regimen, because without it, the results cannot be interpreted accurately. Small antennas printed directly onto the surface of standard capsule can potentially serve as a cost-effective method of validating medication compliance via electronic detection of a swallowed pill in the digestive tract. In this paper, we investigate various aspects of these "electronics pills," including printing methods, conductive inks and radiation characteristics of electrically small antennas inside the human body. We employ realistic antenna models and electromagnetic simulations based on the finite difference time domain method to determine the radiated field intensities for sources in the body. Phantoms solutions with electrical properties that are approximately equivalent to biological tissue are used to experimentally validate simulated results and characterize signal attenuation of electrically small radiation sources in the human torso.
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