{"title":"英夫利昔单抗成功治疗静脉注射抗免疫球蛋白川崎病伴高降钙素原血症1例","authors":"Min Seob Song, Hye Su Hwang","doi":"10.59492/kd.2023.1.1.e9","DOIUrl":null,"url":null,"abstract":"\n\nProcalcitonin (PCT) is modulated by sepsis-related cytokines such as tumor necrosis factor (TNF)-α and interleukins. Therefore, TNF-α blockade, infliximab may be useful for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) with high PCT level. We report a case of IVIG-resistant KD with elevated PCT level who was successfully treated with infliximab. This case report suggests that the treatment of infliximab may be useful for IVIG-resistant KD with high PCT level.\n","PeriodicalId":208326,"journal":{"name":"Kawasaki Disease","volume":"20 4-5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Successful Treatment with Infliximab in Intravenous Immunoglobulin-Resistant Kawasaki Disease with High Procalcitonin Level: A Case Report\",\"authors\":\"Min Seob Song, Hye Su Hwang\",\"doi\":\"10.59492/kd.2023.1.1.e9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nProcalcitonin (PCT) is modulated by sepsis-related cytokines such as tumor necrosis factor (TNF)-α and interleukins. Therefore, TNF-α blockade, infliximab may be useful for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) with high PCT level. We report a case of IVIG-resistant KD with elevated PCT level who was successfully treated with infliximab. This case report suggests that the treatment of infliximab may be useful for IVIG-resistant KD with high PCT level.\\n\",\"PeriodicalId\":208326,\"journal\":{\"name\":\"Kawasaki Disease\",\"volume\":\"20 4-5 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Kawasaki Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.59492/kd.2023.1.1.e9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Kawasaki Disease","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.59492/kd.2023.1.1.e9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Successful Treatment with Infliximab in Intravenous Immunoglobulin-Resistant Kawasaki Disease with High Procalcitonin Level: A Case Report
Procalcitonin (PCT) is modulated by sepsis-related cytokines such as tumor necrosis factor (TNF)-α and interleukins. Therefore, TNF-α blockade, infliximab may be useful for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) with high PCT level. We report a case of IVIG-resistant KD with elevated PCT level who was successfully treated with infliximab. This case report suggests that the treatment of infliximab may be useful for IVIG-resistant KD with high PCT level.