PENTINGNYA MENDETEKSI ORAL LEUKOPLAKIA SEBAGAI ORAL POTENTIALLY MALIGNANT DISORDERS (LAPORAN KASUS)

Oral Leukoplakia (OL) is white plaque lesion in oral mucosa thatcannot be scraped and one of Oral Potentially Malignant Disorder(OPMD) with incidence about 2.5% of all populations in the world.The most case of oral squamous cell carcinoma are preceded byOPMD. The aim of this case report is to understand the importance ofdetection oral lesion that could potentially become malignancy. A 28-year-old male patient complained of sores on his tongue that had nothealed for 2 months. Intraoral examination obtained red and whitelesion on the left lateral tongue: shallow reddish ulcer with irregularborder in region 35-36, followed by unscrapable white plaque lesionwith slight induration in region 37-38. Hematological examinationshowed normal range. According anamnesis and clinical examination,diagnosis of traumatic ulcer and OL were made. Patients were treatedwith multivitamins and antiseptic mouthwash. Histopathologicalexamination results from lesion biopsies show a hyperplastic mass,parakeratosis and a tissue with polymorphic form, a hyperchromaticnucleus of cells associated with histopathologic criteria of squamouscell carcinomas with well differentiation. The patient was referred tothe Hemato-oncology Department for chemotherapy. There are twoimportant parameters should be considered when evaluating thepotential for malignant change of OL that is when finding white lesionswith or without red lesions should always be suspected as OPMD andalways confirm it by histopathological examination as early aspossible. Accurate examination and histopathologic examination isessential to obtain a good prognosis in OPMD.