电心电测量不能预测足月新生儿呼吸窘迫的预后:一项单中心研究

E. Elmazzahy, Salma Elhouchi, E. Khater, K. Ahmed
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The studied parameters were heart rate variability (HRV), cardiac output (CO), cardiac index (CI), stroke volume (SV), stroke index (SI), thoracic fluid content (TFC), stroke volume variation (SVV), index of contractility (ICON), left ventricular (LV) pre-ejection period (PEP), ejection time (ET), and systemic vascular resistance (SVR). Results: The mean ± SD gestational age of the studied group was 38.20 ± 1.19 weeks, weight was 3.03 ± 0.51 kilogram, females were 15 (50%), and males were 15 (50%) which was comparable to the control group (p=0.584), (p=0.284) and (p=0.436) respectively. The mean Apgar score was less among the RD group; at one minute it was 6 and at 5 minutes was 8 (p=0.0001) and (p=0.002). Initial HRV, CO, CI, SV, SI, TFC, SVV, ICON, LV, PEP, ET, and SVR were not different among both groups but there was a significant decrease in CI (p=0.033), HRV (p=0.030), SI (p = 0.017), and SV (p= 0.016) in the RD group after 2 hours. 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引用次数: 0

摘要

当前位置背景:及时处理新生儿呼吸窘迫(RD)可以挽救生命。心电图(EC)不适合诊断,但其在监测心脏参数随时间变化的价值有待验证。工作目的:研究EC血流动力学参数对足月新生儿RD预后的预测能力。采用心电测量法(EC)对30例患有RD的足月新生儿在出生后10分钟及2小时内的血流动力学参数进行了研究,并与另外30例未患RD的足月新生儿进行了比较。研究参数包括心率变异性(HRV)、心输出量(CO)、心脏指数(CI)、脑卒中容积(SV)、脑卒中指数(SI)、胸腔液体含量(TFC)、脑卒中容积变化(SVV)、收缩性指数(ICON)、左心室射血前期(PEP)、射血时间(ET)、和全身血管阻力(SVR)。结果:研究组平均±SD胎龄为38.20±1.19周,体重为3.03±0.51 kg,女性15(50%),男性15(50%),与对照组比较(p=0.584), (p=0.284), (p=0.436)。RD组的平均Apgar评分较低;1分钟时为6,5分钟时为8 (p=0.0001)和(p=0.002)。两组患者初始HRV、CO、CI、SV、SI、TFC、SVV、ICON、LV、PEP、ET、SVR差异无统计学意义,但RD组患者术后2小时CI (p=0.033)、HRV (p=0.030)、SI (p= 0.017)、SV (p= 0.016)均显著降低。在RD患者中,20例(66.6%)好转,10例(33.3%)入住新生儿重症监护室。两组患者HRV、CI、CO、SV、SI、TFC、SVV、PEP、ICON、LVET、SVR在初始和2小时生命评估中具有可比性(p= 0.860)、(p= 0.071)、(p= 0.932)、(p= 0.260)、(p= 0.548)、(p= 0.338)、(p= 0.744)、(p= 0.488)、(p= 0.392)、(p= 0.983)、(p= 0.066)。结论:用心电测量法测定足月新生儿出生10分钟内血流动力学参数与无RD者无显著差异。RD患者2小时心电图不能预测预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Electric Cardiometry is not Predictive of Outcome in Full-term Newborns with Respiratory Distress: A Single Center Study
: Background: Prompt management of respiratory distress (RD) among neonates is lifesaving. Electric cardiometry (EC) is not suitable for diagnosis, but its value in monitoring changes in cardiac parameters over time is in need of verification. Aim of the Work: To study EC hemodynamic parameters predictive ability of outcome in full-term newborns with RD. Materials and Methods: using electric cardiometry (EC) hemodynamic parameters were studied among 30 full term neonates with RD within the first 10 minutes of life and 2 hours later compared to another 30 without RD. The studied parameters were heart rate variability (HRV), cardiac output (CO), cardiac index (CI), stroke volume (SV), stroke index (SI), thoracic fluid content (TFC), stroke volume variation (SVV), index of contractility (ICON), left ventricular (LV) pre-ejection period (PEP), ejection time (ET), and systemic vascular resistance (SVR). Results: The mean ± SD gestational age of the studied group was 38.20 ± 1.19 weeks, weight was 3.03 ± 0.51 kilogram, females were 15 (50%), and males were 15 (50%) which was comparable to the control group (p=0.584), (p=0.284) and (p=0.436) respectively. The mean Apgar score was less among the RD group; at one minute it was 6 and at 5 minutes was 8 (p=0.0001) and (p=0.002). Initial HRV, CO, CI, SV, SI, TFC, SVV, ICON, LV, PEP, ET, and SVR were not different among both groups but there was a significant decrease in CI (p=0.033), HRV (p=0.030), SI (p = 0.017), and SV (p= 0.016) in the RD group after 2 hours. Those with RD, 20 (66.6%) improved and 10 (33.3%) were admitted to the neonatal intensive unit. Both groups with RD had comparable HRV, CI, CO, SV, SI, TFC, SVV, PEP, ICON, LVET, or SVR in initial and the 2 hour of life assessment (p= 0.860), (p= 0.071), (p= 0.932), (p= 0.260), (p= 0.548), (p= 0.338), (p= 0.744), (p= 0.488), (p= 0.392), (p= 0.983), (p= 0.066) respectively. Conclusion: Hemodynamic parameters assessed by electric cardiometry of full term neonates within 10 minutes of birth was not different among those with RD and those without. Electric cardiometry at 2 hours of life of those with RD was not predictive of outcome.
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