金属配合物及其抗COVID-19的潜在治疗作用:药物设计的最新进展

K. Ashiq, Bushra Naureen, Sana Ashiq
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引用次数: 1

摘要

COVID-19是由严重急性呼吸综合征-冠状病毒2 (SARS-CoV-2)引起的全球大流行。由于与高死亡率有关,这次大流行迫使世界上几个国家实施全面封锁,以限制感染的传播。尽管开发了各种疫苗,但仍然迫切需要设计有安全数据支持的新型治疗方法来对抗SARS-CoV-2及其各种突变体。目前,科学家们正在努力寻找新冠肺炎的最佳治疗方案。因此,金属配合物作为有效的抗病毒药物和免疫增强剂对SARS-CoV-2具有很大的潜力。本文就金属配合物对SARS-CoV-2或其靶蛋白的治疗作用和意义进行了探讨。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metal Complexes and Their Potential Therapeutic Role Against COVID-19: Recent Developments in Drug Designing
COVID-19 is a global pandemic caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Being associated with high mortality rates, this pandemic has forced several countries worldwide to impose complete lockdowns to limit the spread of infection. Despite the development of various vaccines, there is still an urgent need to design novel treatments backed with safety data for fighting  SARS-CoV-2 and its various mutants. Currently, scientists are putting their strenuous efforts into finding the best treatment option for COVID-19. In this regard, metal complexes being active antiviral agents and immunity enhancers have great potential against SARS-CoV-2. Herein, metal complexes' therapeutic role and significance against treating SARS-CoV-2 or any of its target proteins are discussed.
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