挖掘与糖尿病相关的基因变异的频繁模式

S. Mutalib, S. A. Rahman, A. Mohamed
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引用次数: 4

摘要

数据挖掘是发现知识和隐藏模式的关键任务,在市场营销、生物医学、药物设计、事件序列等领域具有重要意义。频繁模式挖掘是一种发现新知识或隐藏知识的研究方法。因此,本研究试图通过频繁模式挖掘方法挖掘脱氧核糖核酸(DNA),特别是单核苷酸多态性(SNP),从遗传变异中获得有意义的信息。采用样本枚举算法对糖尿病数据进行了实验。根据我们的实验,发现具有糖尿病风险的遗传变异的支持价值较低。生成的模式提供了信息,可以绘制报告的风险snp与其他未报告的snp之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mining Frequent Patterns for Genetic Variants Associated to Diabetes
Data mining consists of crucial tasks in discovering knowledge and hidden patterns and the tasks are significant in the various areas, such as marketing, biomedical, drugs design, event sequences and etc. Frequent pattern mining is a method that has been explored by a lot of researches in discovering new or hidden knowledge. Therefore, this research attempts to see whether frequent pattern mining method could produce significant information from genetic variants by mining deoxyribonucleic acid (DNA) in particular Single Nucleotide Polymorphism (SNP). The experiments were done using sample enumeration algorithm on diabetes data. Based on our experiments, the genetic variants with diabetes risks were found in low support value. The patterns generated were informative to draw relations between the reported risky SNPs with other unreported SNPs.
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