一种微型超声驱动可编程光遗传植入刺激系统

2016 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS) Pub Date : 2016-04-04 DOI:10.1109/BIOWIRELESS.2016.7445548

Marcus J. Weber, Anirudha Bhat, T. Chang, Jayant Charthad, A. Arbabian

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引用次数: 22

摘要

演示了一种完全可编程、无线供电的光遗传刺激系统。内置光学刺激器的植入式设备使用可编程的外部超声波发射器供电和控制。一个系统的分析进行了调查可获得的光可用功率使用高效超声链路。光强度和光遗传学应用的实际刺激模式很容易实现安全水平的超声波。据我们所知，这是第一个超声波驱动的光基因刺激器。植入装置的有效区域只有15平方毫米。

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A miniaturized ultrasonically powered programmable optogenetic implant stimulator system

A fully programmable, wirelessly powered optogenetic stimulator system is demonstrated. Implantable devices, with integrated optical stimulators, are powered and controlled using a programmable external ultrasonic transmitter. A methodical analysis is performed to investigate obtainable optical available powers using a highly efficient ultrasonic link. Optical intensities and stimulation patterns practical for optogenetic applications are easily achieved with safe levels of ultrasound. To our knowledge, this is the first ultrasonically powered optogenetic stimulator. The active area of the implantable device measures just 15 mm2.

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来源期刊

2016 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS)

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