与择期患者相比,高危急诊心内直视手术患者早期植入体外膜氧合器是否能改善预后?前瞻性队列比较研究。

Ahmed Abdeljawad, Y. Mubarak
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引用次数: 1

摘要

体外膜氧合器(ECMO)已被应用于难治性心脏切开术后心源性休克(PCCS)患者,以维持良好的氧合和血流动力学支持。本研究的目的是比较早期ECMO植入治疗急诊难治性PCCS与选择性单室或双室泵衰竭患者的结果。患者和方法:在2019年1月至2021年6月期间,35例难治性PCCS患者接受了ECMO。患者分为两组:A组为紧急手术18例,B组为选择性手术17例。ECMO通过中央插管(右心房和升主动脉)或外周插管(股血管或腋窝动脉)植入。结果两组患者术前特征、并发症发生率、机械通气时间、ECMO后脱机住院时间、ICU住院时间、住院死亡率、出院人数及随访1年生存率比较,差异均无统计学意义。结论高危急诊心脏手术应尽早考虑ECMO的应用,不要犹豫。急诊和择期患者从ECMO植入中获益相同,并发症发生率相当。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does an Early Implantation of Extracorporeal Membrane Oxygenator in High-Risk Emergency Open Heart Surgery Patients Improve the Outcome in Comparison with Elective Patients? A Prospective Cohort Comparative Study.
BACKGROUND Extracorporeal membrane oxygenator (ECMO) has been implemented in refractory postcardiotomy cardiogenic shock (PCCS) patients to maintain excellent oxygenation and hemodynamic support. The aim of this study is to compare the results of early ECMO implantation to treat refractory PCCS in emergency versus elective patients who developed univentricular or biventricular pump failure. PATIENTS AND METHODS Between January 2019 and June 2021, 35 patients received ECMO after refractory PCCS. Patients have been categorized into two groups: Group A contains 18 patients who were urgently operated on and Group B, which includes 17 patients who were electively operated on. ECMO was implanted through central cannulation (right atrium and ascending aorta), or through peripheral cannulation (femoral vessels or through axillary artery). RESULTS There was no statistically significant difference between the two ECMO groups in the preoperative patient's characteristics, complication rate, duration of mechanical ventilation, post-ECMO weaning hospital stay, duration of ICU stay, in-hospital mortality, and number of patients discharged from the hospital or in 1-year survival on follow up. CONCLUSION Early use of ECMO in high-risk emergency cardiac surgery should be taken into consideration when possible, without hesitance. Emergency and elective patients benefit equally from ECMO implantation and show comparable complication rates.
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