{"title":"猪和大鼠在肝脏脱离循环并受各脏器控制后，其纤溶活性迅速增加。","authors":"K N von Kaulla, E von Kaulla, S Wasantapruek","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Liver-bypass in the pig and the rat instantly results in a marked increase of fibrinolytic activity. Within 1--2 hours this increase is followed in rats by a normalization. A new increase can be obtained by intravenous Carbachol injection. Removal of organs results to various degrees -- most pronounced after bilateral nephrectomy -- in reduction of control value of fibrinolytic activity before liver-bypass. In rats with adrenalectomy plus splenectomy there is no normalization of liver-bypass-induced increased fibrinolytic activity.</p>","PeriodicalId":7089,"journal":{"name":"Acta hepato-gastroenterologica","volume":"26 1","pages":"4-8"},"PeriodicalIF":0.0000,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rapid increase of fibrinolytic activity in pig and rat after exclusion of the liver from the circulation and its control by various organs.\",\"authors\":\"K N von Kaulla, E von Kaulla, S Wasantapruek\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Liver-bypass in the pig and the rat instantly results in a marked increase of fibrinolytic activity. Within 1--2 hours this increase is followed in rats by a normalization. A new increase can be obtained by intravenous Carbachol injection. Removal of organs results to various degrees -- most pronounced after bilateral nephrectomy -- in reduction of control value of fibrinolytic activity before liver-bypass. In rats with adrenalectomy plus splenectomy there is no normalization of liver-bypass-induced increased fibrinolytic activity.</p>\",\"PeriodicalId\":7089,\"journal\":{\"name\":\"Acta hepato-gastroenterologica\",\"volume\":\"26 1\",\"pages\":\"4-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta hepato-gastroenterologica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta hepato-gastroenterologica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Rapid increase of fibrinolytic activity in pig and rat after exclusion of the liver from the circulation and its control by various organs.
Liver-bypass in the pig and the rat instantly results in a marked increase of fibrinolytic activity. Within 1--2 hours this increase is followed in rats by a normalization. A new increase can be obtained by intravenous Carbachol injection. Removal of organs results to various degrees -- most pronounced after bilateral nephrectomy -- in reduction of control value of fibrinolytic activity before liver-bypass. In rats with adrenalectomy plus splenectomy there is no normalization of liver-bypass-induced increased fibrinolytic activity.
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