一种不寻常的横断面结肠癌转移模式:1例报告及文献复习

T. Ejaz
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引用次数: 0

摘要

结直肠癌(Colorectal cancer, CRC)是世界范围内女性发病率第二高、男性发病率第三高的癌症[1]。文献报道,从1992年到2012年,50岁以下男性和女性的CRC发病率以每年2.1%的速度稳步上升[2]。然而,目前不建议对50岁以下的个体进行筛查,除非他们患有炎症性肠病、阳性家族史或易感遗传综合征[3]。crc主要通过淋巴和血液途径传播,较少通过连续和经腹膜传播[2]。在美国,大约20%的患者在发病时已经有远处转移性疾病[2]。最常见的转移部位是肝脏、肺、脑、腹膜和骨骼[2]。大多数crc(60%)最终发展为转移性疾病,仅累及肝脏就占全身转移的近50%[4]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An Unusual Metastatic Pattern of a Transverse Colon Cancer: A Case Report and Review of Literature
Colorectal cancer (CRC) is the second most common cancer in females and the third in males worldwide [1]. The literature reported a steady increase in the incidence of CRC among both males and females under the age of 50 at a rate of 2.1% per year from 1992 through 2012 [2]. Nevertheless, screening is not currently recommended for individuals under the age of 50 unless they have inflammatory bowel disease, a positive family history, or a predisposing inherited syndrome [3]. CRCs spread principally through lymphatic and hematogenous routes, and less commonly by contiguous and trans-peritoneal dissemination [2]. Approximately 20% of patients in the United States have a distant metastatic disease at the time of presentation [2]. The most common reported metastatic sites are the liver, lungs, brain, peritoneum, and bones [2]. Most CRCs (60%) eventually develop metastatic disease, with liver involvement alone accounts for almost 50% of systemic metastasis [4].
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