生物医学用电热驱动SU-8微夹持器的设计

Muhammad Zaeem Abbas, Muhammad Umar Masood, M. M. Saleem, Muhammad Fahad Sheikh
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引用次数: 2

摘要

近几十年来,微操作已成为微机电系统、细胞生物学和细胞力学等领域的重要课题。为了研究细胞力学和细胞生物学,需要样品。一般来说,这些样品是在微钳的帮助下采集的,也被称为微镊子和微机械手。本文提出了一种生物相容性微夹持器设计,用于单细胞操作。由于生物相容性和热性能,选择SU-8材料进行微夹持设计。电热致动器用于向柔性机构提供输入位移和力。柔性机构包括Scott Russell机构、多级复合径向弯曲机构和杠杆机构,在低功率下实现输出位移放大。微夹持器的响应接近线性,可实现精确、智能的操作任务。下巴的设计是为了抓住各种形状和大小的细胞和物体。使用有限元分析软件产生结果,以检查设计对生物医学应用的可用性。在50 mV的低电压下,夹持钳爪的位移达到30 μm,使夹持钳爪的温度保持在室温。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Design of an Electrothermally Actuated SU-8 Based Microgripper for Biomedical Applications
Micromanipulation has become a significant task in the fields of microelectromechanical systems, cell biology and cell mechanics in past few decades. To study cell mechanics and cell biology, samples are required. In general, these samples are taken with the help of a microgripper, also known as micro-tweezer and micromanipulator. In this paper, a biocompatible microgripper design is presented for single cell manipulation. SU-8 material is selected due to biocompatibility and thermal properties for microgripper design. Electrothermal actuators are used to provide input displacement and force to compliant mechanism. Compliant mechanism include Scott Russell mechanism, Multi-stage Compound Radial Flexure and leverage mechanism, which provide amplification in output displacement at low power. Response of microgripper is close to linear for accurate and intelligent manipulation task. Jaws are designed to grip cells and objects of various shapes and sizes. Results are produced using finite element analysis software, to check the usability of design for biomedical applications. 30 μm displacement is achieved at low voltage of 50 mV, keeping temperature of gripping jaws at room temperature.
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