柔性可植入式视网膜假体软微电极的制备与评价

G. Kwon, J. Baek, Seung-Ha Lee, M. Chang, Dong-Cho Lee, Kyung-Sun, Sang-Hoon Lee
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引用次数: 1

摘要

本文提出了一种基于聚二甲基硅氧烷(PDMS)的柔性植入式视网膜假体微电极。在电子束沉积Ti和Au后,通过光刻和化学蚀刻工艺对电极和导线进行图像化处理,并通过电镀工艺制作厚电极。我们通过在ICR小鼠皮肤下植入电极45天,进行了生物相容性评价的体内试验。将电极植入兔眼视网膜下,探讨其作为视网膜假体的可行性
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fabrication and Evaluation of the Flexible and Implantable Soft Micro Electrode for Retinal Prosthesis
This paper presents a polydimethylsiloxane (PDMS)-based flexible and implantable micro electrode for the retinal prosthesis. The patterning of the electrode and the wires was performed through the photolithography and chemical etching process after e-beam deposition Ti and Au, and the thick electrode was fabricated through the electroplating process. We carried out in-vivo test for the evaluation of biocompatibility by implanting electrodes under the ICR mouse skin for 45 days. The electrode was implanted under the retina of rabbit's eye to investigate the feasibility as a retinal prosthesis
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