慢性肾病患者心血管风险与HDL水平降低相关

Silva Cicera Jacqueline da Conceicao, Alencar Rafaely Pereira de, Tenorio Leticia Miranda, Silva Nathanielly Lima da, Barros Amanda Feitosa de, Marinho Chiara Rachel Maciel, Pinto Raphael de Souza
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Cardiovascular Risk in Patients with Chronic Kidney Disease is Associated with Decrease of HDL Levels
Background: Cardiovascular diseases are the leading causes of death in patients with Chronic Kidney Disease (CKD) and several factors are associated with atherosclerosis in this pathology. Objective: We evaluate the metabolic profile from risk factors associated with the development of atherosclerosis in patients with CKD. Method: Biological markers for renal function and associated with atherosclerosis were analyzed from serum samples of 23 patients before undergoing hemodialysis procedure. Results: We observed a correlation of HDL with creatinine. Moreover, a positive correlation was observed between serum albumin levels and the values of VLDL and triglycerides, concomitant with a decrease in HDL. Conclusion: The loss of renal function decreases HDL levels contributing to the development of atherosclerosis in these patients.
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