评价高血压患者对频率、强度和持续时间的差异敏感性

Saranya Mahendran, P. Prabhu
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引用次数: 0

摘要

【摘要】目的高血压是一种血管压力持续升高的疾病。耳蜗的损伤是由于内耳敏感毛细胞的丢失或第八脑神经的损伤。当耳蜗受损时,其编码、分化、时间加工等功能能力都会受到影响。因此,高血压患者的差异敏感性可能存在缺陷。本文的目的是研究高血压对差异敏感性的影响,因为这方面的文献有限。方法将30例受试者分为高血压组和血压正常组,年龄25 ~ 45岁。使用最大似然程序(MLP)工具箱进行频率、强度和时间判别测试等心理物理测试,该工具箱在MATLAB中实现了阈值估计的最大似然程序。结果在500hz、1000hz、2000hz和4000hz的所有频率下,高血压患者的得分均明显低于正常人。这可能是由于频率选择性降低和时间编码差,以及由于高血压患者耳蜗和神经损伤而难以对声音包络随时间的快速变化做出反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Differential Sensitivity for Frequency, Intensity, and Duration in Individuals with Hypertension
Abstract Objective Hypertension is a condition in which the blood vessels have persistently raised pressure. The damage of the cochlea is due to the loss of sensitive hair cells in the inner ear or the damage to the eighth cranial nerve. When the cochlea is damaged, the functioning abilities such as coding, differentiation, and temporal processing abilities will be affected. Hence, there might be deficits in differential sensitivity in individuals with hypertension. The aim of this article was to study the effect of hypertension on differential sensitivity as there is limited literature in this area. Method Thirty participants were included in the study and classified into two groups: group I as individuals with hypertension and group II as individuals with normal blood pressure in the age range of 25 to 45 years. Psychophysical tests like frequency, intensity, and time discrimination tests were performed using the maximum likelihood procedure (MLP) toolbox, which implements a maximum likelihood procedure for threshold estimation in MATLAB. Results In all the three test conditions, the scores were significantly poorer in individuals with hypertension compared with individuals of the normal at all the frequencies such as 500 Hz, 1,000 Hz, 2,000 Hz, and 4,000 Hz. Conclusion This could be because of reduced frequency selectivity and poor temporal coding as well as due to difficulty responding to rapid change in the envelope of sound over time because of cochlear and neural damage in individuals with hypertension.
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