尿石症和肾小管酸中毒。

N. V. Anokhin, M. Prosyannikov, Sergey Golovanov, O. Konstantinova, D. Voytko, A. Sivkov
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引用次数: 0

摘要

介绍。根据泌尿界的传统观念,远端肾小管酸中毒(dRTA)是一种罕见的尿石症患者结石形成的原因。同时,根据最近的研究,特发性钙结石患者不完全dRTA的患病率为16.8%(男性为13.6%,女性为25.5%)。之前,我们发表了一篇综述文章,描述了dRTA的病因和发病机制的特点,并提出了诊断和治疗算法。我们认为有趣的是提出一个临床病例,继续以前的出版物。临床病例。有患者的记忆资料、实验室和仪器分析结果。伴有尿石症和肾小管酸中毒。病人被开了一个长期的保守的柠檬酸盐和噻嗪类利尿剂治疗。在持续治疗的背景下,患者成功实现了血液和尿液主要参数的正常化,疾病稳定缓解。结论:远端肾小管酸中毒合并尿石症在泌尿科临床中较为常见。及时诊断疾病,预约适当的治疗,可以提高患者的生活质量,减少结石复发的次数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Urolithiasis and renal tubular acidosis.
Introduction. Distal renal tubular acidosis (dRTA) is a rare cause of stone formation in urolithiasis patients according to the conventional wisdom in the urological community. At the same time prevalence of the incomplete dRTA in patients with idiopathic calcium stones is 16.8% (13.6% in men and 25.5% in women) according to the recent studies. Previously, we published a review article, which describes the features of the dRTA etiology and pathogenesis, and presents diagnostic and treatment algorithms. We consider it interesting to present a clinical case in continuation of the previous publication. Clinical case. There are anamnesis data, results of laboratory and instrumental analysis of the patient Zh. with a urolithiasis and renal tubular acidosis are presented. The patient was prescribed a long course of conservative citrate and thiazide diuretics therapy. The patient managed to achieve normalization of the main parameters of blood and urine, stable remission of the disease against the background of ongoing therapy. Conclusions, patients with distal renal tubular acidosis and urolithiasis are quite common in the clinical practice of urologist. Timely diagnosis of the disease and the appointment of adequate therapy can improve the quality of patient's life and reduce the number of stone relapses.
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