1%铁丙烯与4%铁丙烯对龈切口后止血效果的比较

A. Tsamarah, Erwid Fatchur Rahman, Rahmawati Sri Praptiningsih
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引用次数: 0

摘要

背景:出血是牙科实践中经常发现的。过多的出血会阻碍伤口愈合。对于外科医生来说,实现快速有效的止血非常重要。因此,局部使用凝血溶液来帮助控制表面出血。一种这样的局部药物是铁丙烯。铁丙烯是一种含有0.05 ~ 0.5%铁的聚丙烯酸聚合物。亚铁元素与白蛋白反应,将水溶性纤维蛋白原转化为不溶于水的纤维蛋白,形成凝块。本研究旨在比较1%阿克瑞姆与4%阿克瑞姆在牙龈切口后止血的效果。方法:本研究为真正意义上的实验研究,共设3个治疗组,即不给药组、给药阿克瑞姆1%组、给药阿克瑞姆4%组,每组9只大鼠。用秒表计算从出血开始到牙龈切口后出血停止的出血时间,并记录。数据分析采用Shapiro-Wilk,齐性检验采用Levene检验,非参数检验采用Kruskal-Wallis和Mann Whitney。结果:结果显示,未使用止血药物组、使用1%阿克瑞姆组和使用4%阿克瑞姆组的平均出血时间分别为221秒、103秒和50秒。Kruskal-Wallis和Mann Whitney的结果显示,两组之间出血时间有显著差异。结论:本研究的结论是,在wistar大鼠的牙龈切口后,应用4%的feracrum比应用1%的feracrum止血更快。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COMPARISON OF THE EFFECTIVENESS OF FERACRYLUM 1% AND FERACRYLUM 4% IN STOPING BLOODING AFTER GINGIVA INCISION
Background: Bleeding is often found in dental practice. Excessive bleeding can hinder wound healing. For the surgeon to achieve rapid and effective hemostasis is important. Therefore, a topical hemocoagulation solution is given to help control surface bleeding by applying it locally. One such topical agent is Feracrylum. Feracrylum is a polymer of polyacrylic acid containing 0.05 to 0.5% iron. Feracrylum iron element will react with albumin and then convert water-soluble fibrinogen into water-insoluble fibrin which then forms a coagulum. This study aims to compare the effectiveness of Feracrylum 1% and Feracrylum 4% in stopping bleeding after gingival incision. Method: This study is a true experimental study that includes 3 treatment groups, namely the group without being given hemostatic agents, the group being given Feracrylum 1%, and the group being given Feracrylum 4%, each group consisting of 9 rats. Data were collected by calculating the bleeding time from the start of bleeding until the bleeding stopped after the gingival incision using a stopwatch and then recorded. Data analysis using Shapiro-Wilk, homogeneity test using Levene Test, nonparametric test using Kruskal-Wallis and Mann Whitney. Result: The results showed that the average bleeding time in the group without hemostatic agents, the group receiving 1% Feracrylum, and the group receiving Feracrylum 4% was 221 seconds, 103 seconds, and 50 seconds. The results of the Kruskal-Wallis and Mann Whitney showed that there was a significant difference in bleeding time between groups. Conclusion: The conclusion of this study is that the application of Feracrylum 4% was faster in stopping bleeding compared to the application of Feracrylum 1% after gingival incision in wistar rats.
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