多细胞生物与癌症

F. Pezzella, D. Kerr, M. Tavassoli
{"title":"多细胞生物与癌症","authors":"F. Pezzella, D. Kerr, M. Tavassoli","doi":"10.1093/MED/9780198779452.003.0001","DOIUrl":null,"url":null,"abstract":"Cancer is a disease of multicellular organisms in which, following the manifestation of genetic alterations, one neoplastic cell develops into a tumour mass which grows escaping all the normal rules of cell coexistence which regulates multicellular organisms. We define as malignant tumour one which spreads throughout the body forming metastases, and as benign tumour one which is localized and non-invasive. Cancer is found mostly throughout the Metazoa (i.e. multicellular animals) but is also present in some plants. A simpler neoplastic-like behaviour, so-called cheating, is present instead even in the simplest multicellular bacterial organisms, where cells can start to grow excessively, escaping normal behaviour.","PeriodicalId":417236,"journal":{"name":"Oxford Textbook of Cancer Biology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The multicellular organism and cancer\",\"authors\":\"F. Pezzella, D. Kerr, M. Tavassoli\",\"doi\":\"10.1093/MED/9780198779452.003.0001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cancer is a disease of multicellular organisms in which, following the manifestation of genetic alterations, one neoplastic cell develops into a tumour mass which grows escaping all the normal rules of cell coexistence which regulates multicellular organisms. We define as malignant tumour one which spreads throughout the body forming metastases, and as benign tumour one which is localized and non-invasive. Cancer is found mostly throughout the Metazoa (i.e. multicellular animals) but is also present in some plants. A simpler neoplastic-like behaviour, so-called cheating, is present instead even in the simplest multicellular bacterial organisms, where cells can start to grow excessively, escaping normal behaviour.\",\"PeriodicalId\":417236,\"journal\":{\"name\":\"Oxford Textbook of Cancer Biology\",\"volume\":\"75 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Textbook of Cancer Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/MED/9780198779452.003.0001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Textbook of Cancer Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/MED/9780198779452.003.0001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

癌症是一种多细胞生物的疾病,在遗传改变的表现之后,一个肿瘤细胞发展成一个肿瘤团块,它的生长摆脱了调节多细胞生物的细胞共存的所有正常规则。我们将扩散到全身形成转移的肿瘤定义为恶性肿瘤,将局部和非侵入性的肿瘤定义为良性肿瘤。癌症主要在后生动物(即多细胞动物)中发现,但也存在于一些植物中。一种更简单的类似肿瘤的行为,即所谓的欺骗,甚至存在于最简单的多细胞细菌有机体中,在那里细胞可以开始过度生长,逃避正常行为。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The multicellular organism and cancer
Cancer is a disease of multicellular organisms in which, following the manifestation of genetic alterations, one neoplastic cell develops into a tumour mass which grows escaping all the normal rules of cell coexistence which regulates multicellular organisms. We define as malignant tumour one which spreads throughout the body forming metastases, and as benign tumour one which is localized and non-invasive. Cancer is found mostly throughout the Metazoa (i.e. multicellular animals) but is also present in some plants. A simpler neoplastic-like behaviour, so-called cheating, is present instead even in the simplest multicellular bacterial organisms, where cells can start to grow excessively, escaping normal behaviour.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信