Multiple Cutaneous Features Associated with Primary Sjogren’s Syndrome

Sjogren’s syndrome is a systemic autoimmune disorder that mainly affects exocrine glands, although the clinical manifestations include both exocrine gland involvement and extraglandular disease features. In addition to dryness, musculoskeletal pain and fatigue are the hallmarks of this disease and constitute the classic symptom triad presented by the vast majority of patients. The authors present the case of a 59-year-old woman with achalasia, sicca syndrome, subcutaneous nodules affecting the knees, purpuric plaques on the palms and vitiligo. Serological tests were consistent with Sjögren′s syndrome, therefore the diagnosis of primary Sjögren’s syndrome with extensive cutaneous manifestations as extraglandular organ involvement was made.