D. Benachenhou, M. Cader, H. Szu, L. Medsker, C. Wittwer, D. Garling
{"title":"利用人工智能专家系统和ART神经网络选择引物,通过聚合酶链反应扩增艾滋病病毒DNA","authors":"D. Benachenhou, M. Cader, H. Szu, L. Medsker, C. Wittwer, D. Garling","doi":"10.1109/CBMSYS.1990.109440","DOIUrl":null,"url":null,"abstract":"To diagnose AIDS patients, doctors are starting to use the methodology of amplification induced by thermal annealing and by adding specific primers to imitate the polymerase chain reaction of the denatured DNA mutated by several types of human immunodeficiency viruses. An adaptive resonance theory (ART) neural network working in concert with an artificial intelligence (AI) rule-based system is shown to be efficient for enhancing the choice of the needed good primers. Because of the tradeoff between the simplicity of primers and the specifics of primers, doctors prefer to diagnose different viral types by administering patients with different sets of good primers. Thus, AI provides ART with both the background for self-organization and the foreground for the final goal.<<ETX>>","PeriodicalId":365366,"journal":{"name":"[1990] Proceedings. Third Annual IEEE Symposium on Computer-Based Medical Systems","volume":"30 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1990-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"AIDS viral DNA amplification by polymerase chain reaction employing primers selected by AI expert system and an ART neural network\",\"authors\":\"D. Benachenhou, M. Cader, H. Szu, L. Medsker, C. Wittwer, D. Garling\",\"doi\":\"10.1109/CBMSYS.1990.109440\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"To diagnose AIDS patients, doctors are starting to use the methodology of amplification induced by thermal annealing and by adding specific primers to imitate the polymerase chain reaction of the denatured DNA mutated by several types of human immunodeficiency viruses. An adaptive resonance theory (ART) neural network working in concert with an artificial intelligence (AI) rule-based system is shown to be efficient for enhancing the choice of the needed good primers. Because of the tradeoff between the simplicity of primers and the specifics of primers, doctors prefer to diagnose different viral types by administering patients with different sets of good primers. Thus, AI provides ART with both the background for self-organization and the foreground for the final goal.<<ETX>>\",\"PeriodicalId\":365366,\"journal\":{\"name\":\"[1990] Proceedings. Third Annual IEEE Symposium on Computer-Based Medical Systems\",\"volume\":\"30 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-06-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"[1990] Proceedings. Third Annual IEEE Symposium on Computer-Based Medical Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CBMSYS.1990.109440\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"[1990] Proceedings. Third Annual IEEE Symposium on Computer-Based Medical Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CBMSYS.1990.109440","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
AIDS viral DNA amplification by polymerase chain reaction employing primers selected by AI expert system and an ART neural network
To diagnose AIDS patients, doctors are starting to use the methodology of amplification induced by thermal annealing and by adding specific primers to imitate the polymerase chain reaction of the denatured DNA mutated by several types of human immunodeficiency viruses. An adaptive resonance theory (ART) neural network working in concert with an artificial intelligence (AI) rule-based system is shown to be efficient for enhancing the choice of the needed good primers. Because of the tradeoff between the simplicity of primers and the specifics of primers, doctors prefer to diagnose different viral types by administering patients with different sets of good primers. Thus, AI provides ART with both the background for self-organization and the foreground for the final goal.<>