钠钾电导分岔检测某些神经系统疾病

Anju Gera, T. Ahmed, Seema Nayak
{"title":"钠钾电导分岔检测某些神经系统疾病","authors":"Anju Gera, T. Ahmed, Seema Nayak","doi":"10.1109/ICDT57929.2023.10150779","DOIUrl":null,"url":null,"abstract":"In neurological research, the HH model and many modified forms have been successfully used to study the neurological dynamics of many neurological and other excitable cell disorders. It has been shown by medical researchers that many neuronal diseases are related to bifurcation of ion channels. For example, sodium channel dynamics are involved in epilepsy, potassium and calcium channels have also been found to be associated with Alzheimer’s disease. It is also known that the threshold for normal spiking requires contribution from both non-linear (voltage-gated Na+ and K+ channels) and linear currents (leak channel). Therefore, study of bifurcation of calcium ion is very important.","PeriodicalId":266681,"journal":{"name":"2023 International Conference on Disruptive Technologies (ICDT)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bifurcation of Sodium and Potassium Conductance for Detection of Some Neurological Disorder\",\"authors\":\"Anju Gera, T. Ahmed, Seema Nayak\",\"doi\":\"10.1109/ICDT57929.2023.10150779\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In neurological research, the HH model and many modified forms have been successfully used to study the neurological dynamics of many neurological and other excitable cell disorders. It has been shown by medical researchers that many neuronal diseases are related to bifurcation of ion channels. For example, sodium channel dynamics are involved in epilepsy, potassium and calcium channels have also been found to be associated with Alzheimer’s disease. It is also known that the threshold for normal spiking requires contribution from both non-linear (voltage-gated Na+ and K+ channels) and linear currents (leak channel). Therefore, study of bifurcation of calcium ion is very important.\",\"PeriodicalId\":266681,\"journal\":{\"name\":\"2023 International Conference on Disruptive Technologies (ICDT)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-05-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2023 International Conference on Disruptive Technologies (ICDT)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICDT57929.2023.10150779\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2023 International Conference on Disruptive Technologies (ICDT)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICDT57929.2023.10150779","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

在神经学研究中,HH模型和许多改进的形式已经成功地用于研究许多神经和其他兴奋性细胞疾病的神经动力学。医学研究表明,许多神经元疾病都与离子通道分叉有关。例如,钠离子通道动力学与癫痫有关,钾离子和钙离子通道也被发现与阿尔茨海默病有关。我们还知道,正常尖峰的阈值需要非线性(电压门控Na+和K+通道)和线性电流(泄漏通道)的贡献。因此,研究钙离子的分岔是非常重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bifurcation of Sodium and Potassium Conductance for Detection of Some Neurological Disorder
In neurological research, the HH model and many modified forms have been successfully used to study the neurological dynamics of many neurological and other excitable cell disorders. It has been shown by medical researchers that many neuronal diseases are related to bifurcation of ion channels. For example, sodium channel dynamics are involved in epilepsy, potassium and calcium channels have also been found to be associated with Alzheimer’s disease. It is also known that the threshold for normal spiking requires contribution from both non-linear (voltage-gated Na+ and K+ channels) and linear currents (leak channel). Therefore, study of bifurcation of calcium ion is very important.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信