1例45岁妇女用皮质类固醇治疗以皮肤表现的IgA血管炎

Vergílio Pereira Carvalho
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引用次数: 0

摘要

免疫球蛋白A血管炎(IgAV)是一种小血管的系统性血管炎。虽然这种情况可能发生在任何年龄组,但这种疾病的流行病学概况主要影响2至10岁的儿科人口。在这个意义上,这篇描述性文章的目的是报告一个罕见的病例,成人患者与IgAV进化,呈现在皮肤形式,并与皮质类固醇治疗。为此,在患者自由知情同意后,本研究获得了里约佛得角大学(UniRV, Goiás,巴西)研究伦理委员会的批准,其伦理考虑陈述证书为36621920.0.0000.507。因此,我们发现患者发展为可能因紫癜和肾脏病变而累及皮肤的IgAV的临床相容性,在非免疫抑制剂量的皮质类固醇治疗中表现出良好的治疗反应,经过1年零3个月的随访,临床症状缓解,没有新的发作。文献中有一些关于非免疫抑制剂量皮质类固醇治疗的良好治疗反应的报道,然而,还需要临床试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
IgA VASCULITIS IN THE FORM OF CUTANEOUS PRESENTATION IN A 45-YEAR-OLD WOMAN TREATED WITH CORTICOSTEROID: CASE REPORT
mmunoglobulin A vasculitis (IgAV) is known to be a systemic vasculitis of small vessels. Although is possible that this condition sets up in any age group, the epidemiological profile of this disease mostly affects the pediatric population between 2 and 10 years of age. In this sense, this descriptive article aims to report the rare case of an adult patient who evolved with IgAV, presented in a cutaneous form, and treated with corticosteroids. For that, after the patient's free and informed consent, the study was approved by the Research Ethics Committee of the University of Rio Verde (UniRV, Goiás, Brazil), whose Certificate of Presentation for Ethical Consideration is 36621920.0.0000.507. Therefore, it was found that the patient evolved with clinical compatible with IgAV of probable cutaneous involvement due to lesions in the form of purpura and renal involvement, presenting a good therapeutic response with corticosteroid therapy at non-immunosuppressive doses and after 1 year and 3 months of follow-up, there was remission of the clinicalpicture without new episodes.There are some reports in the literature about the good therapeutic response of this clinical with corticosteroid therapy at non-immunosuppressive doses, however, clinical trials are needed.
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