辅助研究胸部小活检和细胞学标本的收集和处理:美国病理学家学会(CAP)指南

S. Roy-Chowdhuri
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引用次数: 0

摘要

随着越来越多的临床相关生物标志物需要指导非小细胞肺癌(NSCLC)患者的管理,病理学家敏锐地意识到需要收集足够的组织,不仅用于诊断,而且用于辅助研究,以提供预测和预后信息。通过微创技术采集的小样本,如细针穿刺和核心针活检,往往不能满足肺癌分子生物标志物的充分性要求。美国病理学家学会(CAP)最近发布了一份基于证据的临床实践指南,“收集和处理用于辅助研究的胸部小活检和细胞学标本”,以帮助指导临床医生和病理实验室人员最佳地收集和处理用于辅助测试的胸部小标本。本综述总结了已发表的指南声明,并简要概述了这些建议及其对病理学实践的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies: Guidelines from the College of American Pathologists (CAP)
With a growing number of clinically relevant biomarkers needed to guide the management of patients with non-small cell lung cancer (NSCLC), pathologists are keenly aware of the need to collect adequate tissue not only for a diagnosis, but also for ancillary studies to provide predictive and prognostic information. Small specimens collected by minimally invasive techniques such as fine needle aspiration and core needle biopsy often fall short in meeting adequacy requirements for lung cancer molecular biomarkers. The College of American Pathologists (CAP) recently published an evidence-based clinical practice guideline, “Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies”, to help direct clinicians and pathology laboratory personnel to optimally collect and handle thoracic small specimens for ancillary testing. This review summarizes the published guideline statements and provides a brief overview of the recommendations and how they impact the practice of pathology.
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