哺乳动物同属区二级结构保守元件的鉴定

2011 IEEE International Conference on Systems Biology (ISB) Pub Date : 2011-10-03 DOI:10.1109/ISB.2011.6033182

Toutai Mituyama

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引用次数: 0

摘要

利用先进的RNA序列数据分析工具，从哺乳动物共系中鉴定出3361个假定的RNA二级结构保守区。发现候选基因集中在不同基因的转录因子结合位点，推测二级结构保守元件在转录调控中起一定作用。

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An identification of secondary structure conserved elements in mammalian syntenic regions

3,361 putative RNA secondary structure conserved regions were identified from mammalian syntenies by using leading-edge RNA sequence data analysis tools. The identified candidates are found to be concentrated in transcription factor binding sites of various genes, which infer secondary structure conserved elements play certain roles for transcription regulation.

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2011 IEEE International Conference on Systems Biology (ISB)

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