神经元刺激的电极-组织阻抗非线性分数模型的表征

2013 IEEE Biomedical Circuits and Systems Conference (BioCAS) Pub Date : 2013-12-12 DOI:10.1109/BioCAS.2013.6679708

F. Kölbl, J. Sabatier, G. N'Kaoua, Frederic Naudet, E. Faggiani, A. Benazzouz, S. Renaud, N. Lewis

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引用次数: 6

摘要

神经刺激器的设计必须包括一个真实的电极-组织界面模型。与高水平刺激电流相关的复杂电化学现象使该界面具有分数和非线性行为，而简单的线性化模型无法拟合。本文描述了一种基于双相电流控制请求的测量方案和一种基于多模型的原始方法的建模过程，并考虑了非线性和分数效应。该模型能较好地拟合50μA至1mA电流水平的测量结果。此外，整个表征方案可以安全地转置到体内测量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Characterization of a non linear fractional model of electrode-tissue impedance for neuronal stimulation

The design of neuro-stimulators must include a realistic model of electrode-tissue interface. Complex electrochemical phenomena associated to high levels of stimulation current give fractional and non linear behavior to this interface that simple linearized models fail to fit. This paper describes both a measurement protocol based on biphasic current-controlled solicitations and a modeling procedure relying on an original approach of multi-model, taking into account the non-linear and fractional effects. This model fits correctly the measurement results with current levels varying from 50μA to 1mA. Furthermore the whole characterization protocol can be safely transposed to in vivo measurements.

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2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)

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