出血性中风的危险因素——孟加拉国的病例对照研究

Talha KA, Selina F, Patwary MI, Khan MH, Debnath J
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引用次数: 2

摘要

背景:自发性脑出血是导致死亡和发病的主要原因之一。遗传因素在该病中起重要作用。在非遗传因素中,高血压(HTN)、胰岛素依赖型糖尿病(IDDM)、非胰岛素依赖型糖尿病(NIDDM)、出血性卒中家族史、吸烟、缺血性卒中既往史、饮酒和文化程度是重要因素。方法:本研究的目的是评估脑出血与非遗传危险因素之间的关系。这是一项有120名参与者的病例对照研究。研究地点在Sylhet女子医学院附属医院(SWMCH)神经外科,研究时间为2年。结果:饮酒(RR=3, Odd=3.11)是颅内出血风险最高的人群。其他危险因素为吸烟(RR=2,奇数=2.36)、有脑出血家族史(F/H) (RR=1.3,奇数=1.38)、高血压(RR=1.1,奇数=1.39)、12年级以下文化程度(RR=1.08,奇数=1.63)。IDDM、NIDDM、既往缺血性脑卒中的相对危险度(P/H)均小于1。结论:出血性脑卒中的可控危险因素除遗传因素外很少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk factors of Hemorrhagic Stroke- a Case-Control Study in Bangladesh
Background: Spontaneous intracerebral hemorrhage is one of the leading causes of mortality and morbidity. Genetic factors play an important role in this disease. Among the non-genetic causes Hypertension (HTN), IDDM (insulin dependent diabetes mellitus), NIDDM (non-insulin dependent diabetes mellitus), family history of hemorrhagic stroke, smoking, previous history of ischemic stroke, alcohol intake and education level are important. Methods: The aim of the study was to evaluate the association between ICH and non-genetic risk factors. This was a case-control study with 120 participants. The place of the study was in the Neurosurgery department of Sylhet Women’s Medical College Hospital (SWMCH) and the study period was 2 years. Result: Alcohol consumption (RR=3, Odd=3.11) showed highest risk for ICH. Other risk factors of ICH were smoking (RR=2, Odd=2.36), family history (F/H) of ICH (RR=1.3, Odd=1.38), Hypertension (RR=1.1, Odd=1.39) and below 12 class education status (RR=1.08, Odd=1.63). The relative risk of IDDM, NIDDM, previous history (P/H) of ischemic stroke were less than 1. Conclusion: There are few controllable risk factors of hemorrhagic stroke apart from genetic risk factors.
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