间充质干细胞分类与优化算法性能指标分析

B. Sreedevi, Priya. M Pachaiammal
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引用次数: 1

摘要

干细胞是在所有多细胞生物中发现的生物细胞,它们可以分裂(通过有丝分裂)并分化成各种专门的细胞类型,并且可以自我更新以产生更多的干细胞。优化算法已被证明是许多实际应用的良好解决方案。他们主要受到自然进化的启发。但是,它们仍然面临着陷入局部最小值、收敛速度慢、实现复杂度高等问题。间充质干细胞或基质细胞(MSCs)是维持和修复组织的一部分。功能主要在骨髓源性间充质干细胞中检测。在目前的研究中,通过使用基于图的图像分割来进行分割。通过小波进行特征提取,通过干细胞优化技术进行特征选择。Naïve贝叶斯和支持向量机被用于分类器。结果表明,干细胞优化算法比信息增益(IG)和遗传算法(GA)具有更好的分类精度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of Performance Metrics with Mesenchymal Stem Cell Classification and Optimization Algorithms
Stem cells are biological cells found in all multicellular organisms, that can divide (through mitosis) and differentiate into diverse specialized cell types and can self-renew to produce more stem cells. Optimization algorithms have been proved to be good solutions for many practical applications. They were mainly inspired by natural evolutions. However, they are still faced to some problems such as trapping in local minimums, having low speed of convergence, and also having high order of complexity for implementation. Mesenchymal Stems or stromal Cells (MSCs) are part of maintaining as well as repairing tissues. The functions are mainly examined in bone marrow-derived MSC. In the current study, segmentations are performed through usage of Graph-based image segmentations. Feature extraction is performed through Wavelet while Feature Selection is performed through Stem Cell Optimization techniques. Naïve Bayes as well as Support Vector Machines are utilized for classifiers. Results show that the Stem Cell Optimization has better classification accuracy than Information Gain (IG) and Genetic Algorithm (GA).
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