Yanru Chen, Tianyu Yin, Hang Cui, Miao Wang, T. Jin, Fushun Cui
{"title":"人参浆果多糖体外作用及模拟胃肠消化的研究","authors":"Yanru Chen, Tianyu Yin, Hang Cui, Miao Wang, T. Jin, Fushun Cui","doi":"10.1145/3543081.3543103","DOIUrl":null,"url":null,"abstract":"The physiological activity of ginseng berry polysaccharide (WGBP) extracted by ultrasound and antioxidant activity during simulated gastrointestinal digestion in vitro was studied. The antioxidant activity of WGBP in vitro was studied by DPPH•, ABTS•, •OH scavenging method, and its inhibitory effect on α-glucosidase was analyzed, and antioxidant activity retention rate of WGBP was evaluated by in vitro simulated gas-trointestinal digestion. The results showed that WGBP had strong ability to scavenge DPPH•, ABTS•, and •OH. In the simulation of in vitro gastrointestinal digestion, the retention rates of DPPH•, ABTS•, and •OH scavenging capacity of 5.00 mg/mL WGBP were high after the WGBP was digested for 1 h in the simulated gastric fluid and 2 h in the simulated gastrointesti-nal fluid, which indicated that it still had strong antioxidant activity. In conclusion, WGBP has strong in vitro efficacy, and still has strong antioxidant activity after simulated digestion in vitro.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"30 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study on the Effect and Simulated Gastrointestinal Digestion of Polysaccharide Extracted from Ginseng Berry in Vitro\",\"authors\":\"Yanru Chen, Tianyu Yin, Hang Cui, Miao Wang, T. Jin, Fushun Cui\",\"doi\":\"10.1145/3543081.3543103\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The physiological activity of ginseng berry polysaccharide (WGBP) extracted by ultrasound and antioxidant activity during simulated gastrointestinal digestion in vitro was studied. The antioxidant activity of WGBP in vitro was studied by DPPH•, ABTS•, •OH scavenging method, and its inhibitory effect on α-glucosidase was analyzed, and antioxidant activity retention rate of WGBP was evaluated by in vitro simulated gas-trointestinal digestion. The results showed that WGBP had strong ability to scavenge DPPH•, ABTS•, and •OH. In the simulation of in vitro gastrointestinal digestion, the retention rates of DPPH•, ABTS•, and •OH scavenging capacity of 5.00 mg/mL WGBP were high after the WGBP was digested for 1 h in the simulated gastric fluid and 2 h in the simulated gastrointesti-nal fluid, which indicated that it still had strong antioxidant activity. In conclusion, WGBP has strong in vitro efficacy, and still has strong antioxidant activity after simulated digestion in vitro.\",\"PeriodicalId\":432056,\"journal\":{\"name\":\"Proceedings of the 6th International Conference on Biomedical Engineering and Applications\",\"volume\":\"30 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-05-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 6th International Conference on Biomedical Engineering and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1145/3543081.3543103\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3543081.3543103","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Study on the Effect and Simulated Gastrointestinal Digestion of Polysaccharide Extracted from Ginseng Berry in Vitro
The physiological activity of ginseng berry polysaccharide (WGBP) extracted by ultrasound and antioxidant activity during simulated gastrointestinal digestion in vitro was studied. The antioxidant activity of WGBP in vitro was studied by DPPH•, ABTS•, •OH scavenging method, and its inhibitory effect on α-glucosidase was analyzed, and antioxidant activity retention rate of WGBP was evaluated by in vitro simulated gas-trointestinal digestion. The results showed that WGBP had strong ability to scavenge DPPH•, ABTS•, and •OH. In the simulation of in vitro gastrointestinal digestion, the retention rates of DPPH•, ABTS•, and •OH scavenging capacity of 5.00 mg/mL WGBP were high after the WGBP was digested for 1 h in the simulated gastric fluid and 2 h in the simulated gastrointesti-nal fluid, which indicated that it still had strong antioxidant activity. In conclusion, WGBP has strong in vitro efficacy, and still has strong antioxidant activity after simulated digestion in vitro.