全基因组测序在医学应用中的进展

M. Wagner, D. Benjamin
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引用次数: 0

摘要

目前,仍有许多疾病的发病机制不清楚,但利用新一代测序技术对生物体进行全基因组测序,这为许多疾病的发病机制提供了新的理论依据。那么,全基因组测序在医学上的应用有哪些方面?在本文中,我通过阅读国外近五年关于全基因组测序的研究论文,发现全基因组测序可以广泛应用于遗传病、肿瘤、传染病、传染病流行、判断个体对疾病的易感性、生物进化等多种疾病的诊断和治疗。本文综述了全基因组测序在医学上的应用进展,从遗传病、肿瘤、传染病、传染病流行、确定个体易感性和生物进化等方面进行了综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Whole Genome Sequencing Progress in Medical Application
At present, there are still a lot of diseases pathogenesis not clear, but making use of a new generation of sequencing technology to organisms conduct whole genome sequencing, which for the pathogenesis of many diseases provide a new theoretical basis. So, Which aspects the whole genome sequencing in medical use? In this article, I got through reading the whole genome sequencing of research papers about abroad nearly five years finding that the whole genome sequencing could be widely used in genetic disease, tumor, infectious diseases, infectious epidemic, judge the individual susceptibility to disease, the diagnosis and treatment of a variety of diseases such as biological evolution. This paper reviewed the whole genome sequencing progress in medical application from a genetic disease, tumor, infectious diseases, infectious epidemic, determine the individual susceptibility and biological evolution.
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