空肠浆膜贴片术:一种治疗消化性溃疡穿孔的成功技术

A. Bekele, S. Kassa, Mulat Taye
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引用次数: 4

摘要

背景:选择最合适的技术来修复消化性溃疡穿孔,特别是当最初的闭合尝试失败时,一直是许多外科医生关注的问题。自1963年Koboldin关于空肠浆膜贴片手术的实验报告以来,作者报道了其使用效果令人鼓舞。本文的主要目的是描述我们的经验,空肠浆膜补片手术失败的患者大网膜补片手术后穿孔性消化性溃疡疾病。方法:回顾性报告了在埃塞俄比亚亚的斯亚贝巴Minilik II医院对穿孔性消化性溃疡最初实施带蒂网膜补片手术失败的病例,这些病例随后接受了空肠补片手术。详细介绍他们的手术过程,并发症的观察和结果。结果:纳入5例患者,均为男性,平均年龄32.2岁(范围31-40岁)。所有患者首次手术前的病程为48- 360小时(平均153.6小时)。所有患者在第一次手术时腹膜有明显的胃和化脓性物质收集,穿孔的平均大小为1.3 cm(范围1-2cm)。5例患者均在平均76.8小时后再次手术,均行十二指肠穿孔修补术。1例空肠补片术后24小时内再次手术,4例术后24小时内再次手术(平均34.8小时)。网膜贴片4例完全脱离,1例部分脱离。所有患者均采用标准化空肠网膜贴片治疗。术后5例患者共出现16例并发症。一名患者死亡,总死亡率为20%。平均住院时间25.5天(范围17- 51天),平均25.4天。结论:网膜补片渗漏的治疗难度较大。虽然一些渗漏会转变成瘘管,并在长时间的高营养和持续的护理后最终闭合,但这种方法需要延长住院时间,相关的发病率、死亡率和患者的经济/社会消耗是巨大的。另一方面,通过浆液修补迅速关闭这些缺陷可导致液体和电解质迅速恢复正常,并允许早期口服喂养。我们有限的经验是令人鼓舞的,我们的术后并发症和死亡率在可接受的范围内。我们相信这个程序是可学习的,并且有潜力用于涉及GIT其他部分的困难穿孔。关键词:空肠,浆膜,补片,穿孔,消化性溃疡
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Jejunal Serosal Patch Procedure: A Successful Technique for Managing Difficult Peptic Ulcer Perforation
Background: The selection of the most appropriate technique for the repair of peptic ulcer perforations, especially when the initial attempt of closure has failed have been the concern of many surgeons. Since the experimental report regarding the jejunal serosal patch procedure by Koboldin in 1963, authors have reported its use with encouraging outcome. The main objective of this paper is to describe our experience with the Jejunal Serosal Patch procedure in patients with failed Omental patch procedure following perforated peptic ulcer disease. Methods: This is a retrospective report of cases with failed pedicled omental patch procedure initially performed for perforated peptic ulcer disease and who subsequently underwent Jejunal Patch Procedure at the Minilik II Hospital in Addis Ababa, Ethiopia. Details of their surgical procedure, complications observed and outcome is presented. Results: Five patients, who are all male with mean age of 32.2 years (Range= 31-40 years) were included in the study. The duration of illness of all patients before their first surgery ranged from 48- 360 hours (mean= 153.6 hours). All patients had significant collection of gastric and purulent material in the peritoneum during the first surgery and the mean size of the perforation was 1.3 cm (Range 1-2cm). All five patients were re-operated for the first time after a mean of 76.8 hours and all were managed with re-patching of the duodenal perforation. The second re-operation for jejunal patch procedure was within 24 hours in one patient and > 24 hours in four patients (Mean=34.8 hours). The omental patch was found completely detached in 4 patients and partially separated in one. All patients were treated in a similar fashion by using a standardized Jejunal omental patch procedure. Post operatively, a total of 16 complications were seen in the five patients. One patient died, yielding an overall mortality rate of 20%. The mean hospital stay was 25.5 days of (Range 17- 51 days) mean 25.4 days. Conclusion: The management of the leaking omental patch is very difficult. Although some leaks transform into fistulas and will eventually close after prolonged period of hyperalimentation and continuous nursing care, this approach requires extended hospitalization and the associated morbidity, mortality and financial/social depletion on the patient is enormous. On the other hand, prompt closure of these defects by serosal patching can result in a rapid return of fluid and electrolytes to normal and permits early oral feedings. Our limited experience with this procedure is encouraging and our post operative complications and mortality are within the acceptable range. We believe this procedure is learnable, and has the potential to be utilised in difficult perforations involving the other parts of the GIT. Key words : Jejunal, Serosal, Patch Procedure, perforation, peptic ulcer
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