A 3-D computer simulation study of body surface Laplacian maps during ventricular activation

The goal of this study was to evaluate the spatial resolution of body surface Laplacian maps (BSLMs) to localize ventricular electrical activity on the anterior wall of the heart by means of computer simulation. A 3-D computer heart-torso model was used to simulate cardiac electrical activity, BSLMs and body surface potential maps (BSPMs). A two site pacing protocol was used to generate two simultaneous myocardial events on the anterior epicardial wall, and on the anterior endocardial wall. The BSLM showed better performance as compared with the BSPM for localizing initial ventricular activation following two site pacing. The present study suggests that body surface Laplacian mapping merits further investigation to explore its application to the clinical diagnosis of cardiac abnormalities.<>