O. I. Pikhur, D. S. Tishkov, S. Grechikhin, A. Gromov, Yuliya V. Plotkina, A. M. Kulkov
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引用次数: 0
摘要
的相关性。牙瘤是由牙组织成分组成的良性牙源性肿瘤。牙瘤的诊断和鉴别诊断非常复杂,因为牙瘤具有高度的异质性和显著的形态异质性。临床病例描述。本文介绍了利用光学显微镜、扫描电子显微镜、x射线计算机显微断层扫描和显微探针分析等综合研究方法,对一名7岁患者因医学原因手术切除的牙瘤的形态和组成进行研究的结果。本研究确定该牙瘤属于实心单纯性牙瘤。牙瘤大小为0.93 cm ~ 0.63 cm ~ 0.45 cm,由牙本质覆盖一层不规则的牙釉质表面形成。显微断层扫描提供了牙瘤内部结构的3D模型,显示了由硬牙组织形成的锥形腔。牙瘤的化学成分中含有大量的钙、磷、钠、镁和氯。牙本质Ca/ p系数为1.44,牙釉质Ca/ p系数为- 1.66 ~ 1.68。研究结果有助于探究牙瘤的病因及发病机制,为病理诊断和实施治疗预防措施提供依据。
Morphological structure and composition of an odontoma removed from a 7-year-old child: a clinical case
Relevance. An odontoma is a benign odontogenic tumour that consists of dental tissue elements. Diagnosis and differential diagnosis of odontomas is complicated enough for their high heterogeneity and significant morphological inhomogeneity.Clinical case description. The article presents the results of studying the morphology and composition of odontoma removed surgically for medical reasons in a 7-year-old patient using a complex of the following research methods: optical microscopy, scanning electron microscopy, X-ray computed microtomography and microprobe analysis. The study established that the odontoma belongs to solid simple odontoma. The odontoma is 0.93 х 0.63 х 0.45 cm in size and formed by dentin covered with an uneven layer of the irregular enamel surface. The microtomography provided the odontoma's internal structure 3D model demonstrating a conical cavity formed by the hard dental tissues. The chemical composition of odontoma contains significant amounts of calcium, phosphorus, sodium, magnesium, and chlorine. The Ca/P-coefficient in dentin is 1.44, and in enamel – 1.66-1.68.Conclusion. The study results contribute to the odontoma causes and pathogenesis investigation and form the base for the pathology diagnosis and implementation of treatment and preventive measures.