用于非侵入性癌症治疗的亚纳秒脉冲强电磁场辐射器

2015 International Conference on BioSignal Analysis, Processing and Systems (ICBAPS) Pub Date : 2015-05-26 DOI:10.1109/ICBAPS.2015.7292212

A. Petrishia, M. Sasikala

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引用次数: 1

摘要

生物电磁学的研究已进入亚纳秒脉冲电场治疗癌细胞的范围。脉冲辐射天线(IRA)适用于辐射亚纳秒级电磁脉冲，用于无创治疗皮肤癌。反射式脉冲辐射天线(IRA)的馈源是一种超宽带天线。亚纳秒电脉冲从第一焦点辐射，并聚焦在放置目标(肿瘤)的第二焦点上。在这项工作中，设计了两种类型的散热器。设计了椭圆形角(EPH)进给的长形球面反射器(PSR)和斜丝双锥(SWB)进给的长形球面反射器(PSR)。给出了设计参数和辐射性能。从天线发射的持续时间为100ps的电脉冲导致膜的充电和纳米孔的形成，这是对细胞的主要生物电效应。孔隙的大小通过重复脉冲而增加。多重脉冲对细胞造成不可逆损伤。

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Subnanosecond pulsed intense electromagnetic field radiators for non-invasive cancer treatment

The research of Bio-Electromagnetics has moved in to a range of subnanosecond pulsed electric field to treat cancer cells. The Impulse Radiating Antenna (IRA) is suited for radiating subnanosecond electromagnetic impulse for the treatment of skin cancer noninvasively. The feed of the reflector Impulse Radiating Antenna (IRA) is an ultra-wideband antenna. The subnanosecond electric pulse is radiated from the first focal point and is focused at the second focal point where the target (tumor) is placed. In this proposed work, two types of radiators are designed. The Prolate Spheroidal Reflector (PSR) with Elliptic Profile Horn (EPH) feed and the Prolate Spheroidal Reflector (PSR) with Slanted Wire Bicone (SWB) feed are designed. The design parameters and radiation performance are presented. The radiated electric pulse from the antenna with duration of 100ps, results in charging of membrane and the formation of nano pore which are the dominant bioelectric effects on cells. The size of the pore is increased by repetitive pulsing. Irreversible damage of cell is caused by multiple pulses.

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2015 International Conference on BioSignal Analysis, Processing and Systems (ICBAPS)

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