{"title":"电子鼻的化学感觉适应","authors":"R. Gutierrez-Osuna, Nilesh U. Powar, P. Sun","doi":"10.1109/BIBE.2001.974433","DOIUrl":null,"url":null,"abstract":"This article presents a computational mechanism inspired by the process of chemosensory adaptation in the mammalian olfactory system. The algorithm operates on multiple subsets of the sensory space, generating a family of discriminant functions for different volatile compounds. A set of selectivity coefficients is associated to each discriminant function on the basis of its behavior in the presence of mixtures. These coefficients are employed to form a weighted average of the discriminant functions and establish a feedback signal that reduces the contribution of certain sensory inputs, inhibiting the overall selectivity of the system to previously detected analytes. The algorithm is validated on a database of organic solvents using an array of temperature-modulated metal-oxide chemoresistors.","PeriodicalId":405124,"journal":{"name":"Proceedings 2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering (BIBE 2001)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2001-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Chemosensory adaptation in an electronic nose\",\"authors\":\"R. Gutierrez-Osuna, Nilesh U. Powar, P. Sun\",\"doi\":\"10.1109/BIBE.2001.974433\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This article presents a computational mechanism inspired by the process of chemosensory adaptation in the mammalian olfactory system. The algorithm operates on multiple subsets of the sensory space, generating a family of discriminant functions for different volatile compounds. A set of selectivity coefficients is associated to each discriminant function on the basis of its behavior in the presence of mixtures. These coefficients are employed to form a weighted average of the discriminant functions and establish a feedback signal that reduces the contribution of certain sensory inputs, inhibiting the overall selectivity of the system to previously detected analytes. The algorithm is validated on a database of organic solvents using an array of temperature-modulated metal-oxide chemoresistors.\",\"PeriodicalId\":405124,\"journal\":{\"name\":\"Proceedings 2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering (BIBE 2001)\",\"volume\":\"24 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2001-03-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings 2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering (BIBE 2001)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/BIBE.2001.974433\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings 2nd Annual IEEE International Symposium on Bioinformatics and Bioengineering (BIBE 2001)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BIBE.2001.974433","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
This article presents a computational mechanism inspired by the process of chemosensory adaptation in the mammalian olfactory system. The algorithm operates on multiple subsets of the sensory space, generating a family of discriminant functions for different volatile compounds. A set of selectivity coefficients is associated to each discriminant function on the basis of its behavior in the presence of mixtures. These coefficients are employed to form a weighted average of the discriminant functions and establish a feedback signal that reduces the contribution of certain sensory inputs, inhibiting the overall selectivity of the system to previously detected analytes. The algorithm is validated on a database of organic solvents using an array of temperature-modulated metal-oxide chemoresistors.