C57BL/6J小鼠脑MRI模板及图谱工具箱

Lan Lin, Kewei Chen, J. Valla, Jiping He, E. Reiman, J. Galons, B. Hauss-Wegrzyniak, G. Alexander
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引用次数: 3

摘要

为了比较不同受试者的脑成像测量结果,通常使用脑映射算法将个体大脑注册到标准化的脑图谱上。本研究利用SPM99对Paxinos和Franklin(2001)的C57BL/6J空间标准化t2加权模板进行了线性和非线性共配,评价了图谱与模板之间的局部精度,并开发了工具箱。本研究为小鼠脑图像的兴趣区分析奠定了基础
本文章由计算机程序翻译,如有差异,请以英文原文为准。
MRI Template and Atlas Toolbox for the C57BL/6J Mouse Brain
In order to compare brain-imaging measurements from different subjects, brain-mapping algorithms are commonly used to register individual brain onto a standardized brain atlas. In this study, SPM99 was used to linearly and nonlinearly coregister a spatially standardized T2-weighted template of C57BL/6J to the atlas by Paxinos and Franklin (2001), local accuracy of between atlas and template was evaluated, and a toolbox was developed. This study provides a foundation for the region of interest analysis for mouse brain images
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