{"title":"硬膜外盐水冲洗对0.5%布比卡因硬膜外麻醉的逆转作用","authors":"Jadeny Sinatra, Reuben Policarpio","doi":"10.46880/ijbhm.v1i1.730","DOIUrl":null,"url":null,"abstract":"Background: Prolonged motor and sensory block following epidural anesthesia has been associated with patient dissatisfaction. Administration of epidural crystalloids in patient who had received bupivacaine 0.75% and lidocaine 2% epidural anesthesia. However, bupivacaine 0.5% is commonly used in our institutional and the effectiveness of bolus of NS in non-obstetrical patients undergoing 0.5% bupivacaine epidural anesthesia has not been investigated. The objective of this study was to determine the relationship of normal saline (NS) epidural flush volume to the recovery of motor and sensory block and its hemodynamic stability (blood pressure and heart rate) in non-obstetrical patients undergoing epidural anesthesia using 0.5% bupivacaine. Methods: Following surgery, subjects with T6 dermatome level of sensory, were randomized to 2 treatment groups. Group 1 (control, n = 11) received 1-mL epidural normal saline (NS). Group 2 (experimental, n = 11) received an epidural bolus of 30-mL NS. Assesment of motor and sensory block was performed at 15-minute intervals until complete motor and sensory recovery. Hemodynamic stability (blood pressure and heart rate) between two groups were also monitor every 15-minutes and determined. Results: Times to full motor recovery were significantly faster in the epidural bolus of 30-mL groups than in the control group (69 ± 19.66 vs 95 ± 11.83; p = 0.0017).). Conclusions: A more rapid recovery of motor block in patients undergoing 0.5% bupivacaine epidural anesthesia can be achieved with the use of 30-mL NS epidural washout, with hemodynamic stability.","PeriodicalId":422367,"journal":{"name":"International Journal of Biomedical Herbal Medicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reversal of Bupivacaine 0.5% Epidural Anesthesia Using Epidural Saline Washout\",\"authors\":\"Jadeny Sinatra, Reuben Policarpio\",\"doi\":\"10.46880/ijbhm.v1i1.730\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Prolonged motor and sensory block following epidural anesthesia has been associated with patient dissatisfaction. Administration of epidural crystalloids in patient who had received bupivacaine 0.75% and lidocaine 2% epidural anesthesia. However, bupivacaine 0.5% is commonly used in our institutional and the effectiveness of bolus of NS in non-obstetrical patients undergoing 0.5% bupivacaine epidural anesthesia has not been investigated. The objective of this study was to determine the relationship of normal saline (NS) epidural flush volume to the recovery of motor and sensory block and its hemodynamic stability (blood pressure and heart rate) in non-obstetrical patients undergoing epidural anesthesia using 0.5% bupivacaine. Methods: Following surgery, subjects with T6 dermatome level of sensory, were randomized to 2 treatment groups. Group 1 (control, n = 11) received 1-mL epidural normal saline (NS). Group 2 (experimental, n = 11) received an epidural bolus of 30-mL NS. Assesment of motor and sensory block was performed at 15-minute intervals until complete motor and sensory recovery. Hemodynamic stability (blood pressure and heart rate) between two groups were also monitor every 15-minutes and determined. Results: Times to full motor recovery were significantly faster in the epidural bolus of 30-mL groups than in the control group (69 ± 19.66 vs 95 ± 11.83; p = 0.0017).). Conclusions: A more rapid recovery of motor block in patients undergoing 0.5% bupivacaine epidural anesthesia can be achieved with the use of 30-mL NS epidural washout, with hemodynamic stability.\",\"PeriodicalId\":422367,\"journal\":{\"name\":\"International Journal of Biomedical Herbal Medicine\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Biomedical Herbal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46880/ijbhm.v1i1.730\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Biomedical Herbal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46880/ijbhm.v1i1.730","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:硬膜外麻醉后长时间的运动和感觉阻滞与患者的不满意有关。布比卡因0.75%、利多卡因2%硬膜外麻醉患者硬膜外晶体的应用。然而,0.5%布比卡因在我们的机构中被广泛使用,对于接受0.5%布比卡因硬膜外麻醉的非产科患者,大剂量NS的有效性尚未被调查。本研究的目的是确定生理盐水(NS)硬膜外冲洗量与0.5%布比卡因硬膜外麻醉非产科患者运动和感觉阻滞恢复及其血流动力学稳定性(血压和心率)的关系。方法:手术后将感觉水平为T6的受试者随机分为2个治疗组。1组(对照组11例)给予硬膜外生理盐水1 ml。第二组(实验组,n = 11)给予30 ml NS硬膜外灌注。每隔15分钟评估一次运动和感觉阻滞,直到运动和感觉完全恢复。每隔15分钟监测两组间血流动力学稳定性(血压、心率)。结果:30 ml硬膜外注射组达到运动完全恢复所需时间明显快于对照组(69±19.66 vs 95±11.83;P = 0.0017)。结论:使用30ml NS硬膜外冲洗液可使0.5%布比卡因硬膜外麻醉患者的运动阻滞更快恢复,且血流动力学稳定。
Reversal of Bupivacaine 0.5% Epidural Anesthesia Using Epidural Saline Washout
Background: Prolonged motor and sensory block following epidural anesthesia has been associated with patient dissatisfaction. Administration of epidural crystalloids in patient who had received bupivacaine 0.75% and lidocaine 2% epidural anesthesia. However, bupivacaine 0.5% is commonly used in our institutional and the effectiveness of bolus of NS in non-obstetrical patients undergoing 0.5% bupivacaine epidural anesthesia has not been investigated. The objective of this study was to determine the relationship of normal saline (NS) epidural flush volume to the recovery of motor and sensory block and its hemodynamic stability (blood pressure and heart rate) in non-obstetrical patients undergoing epidural anesthesia using 0.5% bupivacaine. Methods: Following surgery, subjects with T6 dermatome level of sensory, were randomized to 2 treatment groups. Group 1 (control, n = 11) received 1-mL epidural normal saline (NS). Group 2 (experimental, n = 11) received an epidural bolus of 30-mL NS. Assesment of motor and sensory block was performed at 15-minute intervals until complete motor and sensory recovery. Hemodynamic stability (blood pressure and heart rate) between two groups were also monitor every 15-minutes and determined. Results: Times to full motor recovery were significantly faster in the epidural bolus of 30-mL groups than in the control group (69 ± 19.66 vs 95 ± 11.83; p = 0.0017).). Conclusions: A more rapid recovery of motor block in patients undergoing 0.5% bupivacaine epidural anesthesia can be achieved with the use of 30-mL NS epidural washout, with hemodynamic stability.