杜阿拉-喀麦隆部分医院粪便中肠炎细菌的流行病学及敏感性分析

Raphael Tchientcheu, C. Penda, Rébecca Madeleine Ebelle Etame, Colette Grace Ngondi Dalle, R. S. Mouokeu, Rosalie Annie Ngono Ngane
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引用次数: 1

摘要

背景:细菌引起的肠胃炎是一个严重的公共卫生问题。抗生素耐药性很常见。这项工作描述了在喀麦隆杜阿拉参与胃肠道感染的细菌的流行病学和耐药概况。方法:于2017年3月至12月对粪便样本进行横断面研究。通过形态学、生化和生理试验对细菌种类进行了诊断。采用纸片扩散法对15种常用抗生素的耐药情况进行了调查。结果:250份粪便标本中阳性206份,其中1种细菌129份(62.62%),1种以上细菌77份(37.38%)。共检出病原菌301种,其中大肠杆菌占1 / 3以上(33.89%),其次为肺炎克雷伯菌(22.26%)、产气肠杆菌(11.96%)、沙门氏菌(10.30%)、弗氏柠檬酸杆菌(9.97%)、小肠结肠炎耶尔森菌(4.65%)、福氏志贺氏菌(3.99%)、粘质沙雷氏菌(2.33%)和变形杆菌(0.66%)。抗生素谱显示对四环素、阿莫西林、阿莫西林+克拉维酸、强力霉素和复方新恶唑耐药。结论:本研究结果为杜阿拉地区胃肠道感染的控制提供了新的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiology and Sensibility Profile of Some Enteric Bacteria Isolated from Stool Samples in Some Douala-Cameroon Hospitals
Background: Gastroenteritis caused by bacteria are a serious public health issue. Antibiotic resistance is common. This work described the epidemiological and resistance profile of bacteria involved in gastrointestinal infection in Douala, Cameroon. Methods: A cross-sectional study was conducted from March to December 2017 on stool samples. Bacterial species were diagnosed on the basis of morphological, biochemical and physiological tests. The resistance profile on fifteen routine antibiotics was investigated using the disks diffusion method. Results: Out of 250 stool samples examined, 206 were positive, 129 (62.62%) samples had only one bacterial species and 77 (37.38%) more than one species. 301 pathogenic bacteria were identified of which Escherichia coli represented more than one third (33.89%), followed by Klebsiella pneumoniae (22.26%), Enterobacter aerogenes (11.96%), Salmonella sp (10.30%), Citrobacter freundii (9.97%), Yersinia enterocolitica (4.65%), Shigella flexneri (3.99%), Serratia marcescens (2.33%) and Proteus sp (0.66%). The antibiogram showed high resistance to Tetracycline, Amoxycillin, Amoxycillin + clavulanic acid, Doxycycline and Cotrimoxazol. Imipenem and Amikacin were the most active Conclusion: The present findings provide additional information for the control of gastrointestinal tract infections in Douala.
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