42岁男性肝脏巨海绵状血管瘤的症状

A. Dambatta
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摘要

大多数肝血管瘤是在肝脏超声或计算机断层扫描中偶然发现的。然而,巨大海绵状血管瘤(GCH)在临床上与较小的无症状血管瘤不同,可能与原发性或转移性恶性肿瘤混淆。有症状的肝脏GCH是罕见的。本研究的目的是显示罕见的肝脏巨海绵状血管瘤的症状,它可能与原发性或转移性恶性肿瘤混淆。回顾和总结患者的图像(腹部超声和计算机断层扫描)和病例档案。本文对巨海绵状血管瘤的主题作一综述。对指标病例进行了讨论,并与文献进行了比较。我们报告一位42岁的男性,他有2年的右上腹部疼痛史和6个月的胸痛史。无黄疸、身体肿胀史,无输血史。没有吸烟或饮酒史。该患者是已知的糖尿病患者。腹部超声显示肝脏肿大,有一个巨大的清晰的椭圆形混合回声肿块,分叶状边缘占据肝脏第4和第5段,大小为84.9×111 mm,提示腺瘤。其余肝实质正常。未见肝内胆道扩张。初步组织学检查显示为腺瘤。后来复查组织学检查显示为肝炎。随后进行腹部CT扫描,显示肝脏肿大,但在对比前图像上没有明显的肿块病变。然而,增强图像显示相当圆形的肿块病变,周围增强,静脉期延迟充盈,可见右肺叶上方延伸至穹状部。肝内血管和胆管未扩张。海绵状血管瘤的诊断是基于延迟(向心)填充的标准。然而,该患者未能随访。肝血管瘤可以是巨大和有症状的,尽管它很罕见,但在实践中仍然可能遇到。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Symptomatic giant cavernous hemangioma of the liver in a 42-year-old man
Most cases of liver hemangioma are asymptomatic and discovered incidentally on liver ultrasound or computed tomography scan. Giant cavernous hemangioma (GCH) are however clinically distinct from smaller asymptomatic ones and may be confused with primary or metastatic malignancy. Symptomatic GCH of the liver are rare. The aim of the study was to show the rare case of symptomatic giant cavernous hemangioma of the liver which may be confuse with primary or metastatic malignancy. The patient’s images (abdominal ultrasound and computed tomography scans) and case file were reviewed and summarized. The subject matter of giant cavernous hemangioma was reviewed in the literature. The index case was discussed and compared with literature. We report a 42-year-old man who presented with a 2-year history of right upper abdominal pain and 6-month history of chest pain. No history of jaundice, body swelling or previous history of blood transfusion. No history of smoking or alcohol consumption. The patient is a known diabetic. Abdominal ultrasound scan showed hepatomegaly with a huge well defined oval shaped mixed echogenic mass lesion with lobulated margins occupying 4th and 5th segments of liver, measuring 84.9×111 mm in size suggestive of adenoma. The remaining hepatic parenchyma was normal. No intrahepatic biliary dilatation was seen. Initial histological examination revealed adenoma. Repeat histology done later however revealed hepatitis. Abdominal CT scan was later carried out and showed hepatomegaly but with no discernible mass lesion on precontrast images. Contrast enhanced images however, showed a fairly rounded mass lesion with peripheral enhancement and delayed filling-in at the venous phase, seen in the superior aspect of the right lobe extending to the dome. The intrahepatic vasculature and biliary ducts are not dilated. A diagnosis of cavernous hemangioma was made based on criteria of delayed (centripetal) filling-in. The patient however was lost to follow up. Hepatic hemangioma can be giant and symptomatic and despite its rarity, may still be encountered in practice.
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