伊朗萨里伊玛目霍梅尼医院新冠肺炎住院患者肾功能评估

A. Makhlough, Zahra Hamidi Nava
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摘要

背景:2019年12月以来,2019冠状病毒病(COVID-19)已成为一个全球性的健康问题。这种疾病主要针对呼吸系统,但也可能损害患者身体的其他器官,如肾脏。目的:本研究的主要目的是确定伊朗萨里伊玛目霍梅尼医院收治的COVID-19患者的肾功能。方法:本研究为横断面型,统计样本为伊朗萨里市伊玛目霍梅尼医院住院的498例新冠肺炎患者。为了进行这项研究,我们收集了患者的人口学、临床和实验室信息,并将这些信息记录在研究者制作的检查表中。患者分为三个阶段(研究开始、住院第3天和住院第6天)进行评估。最后,记录上述每个步骤的结果。结果:女性患者占49.6%(247人),男性患者占50.4%(251人)。根据结果,患者的平均年龄为55.2岁。在肾脏疾病中,慢性肾脏疾病(CKD)发病率最高(25.9%)。根据肾脏疾病:改善全球预后(KDIGO), 12.9%的患者有急性肾损伤(AKI)。肾脏疾病的存在和AKI的发展与重症监护病房(ICU)的需要有显著关系(P < 0.05)。结果显示,虽然最初肾脏疾病与ICU转院有显著关系(P < 0.05),但在去除年龄、性别变量的影响后,这种关系不显著(P > 0.05)。结论:根据本研究结果,肾衰竭等基础疾病可非常有效地感染COVID,并增加其严重程度,因此有必要采取预防措施并对这些患者进行特殊护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Kidney Function in Patients with COVID-19 Hospitalized in Imam Khomeini Hospital, Sari, Iran
Background: The 2019 coronavirus disease (COVID-19) has become a worldwide health problem since December 2019. This disease mainly targets the respiratory system, but it may also damage other organs of the patient's body, such as the kidney. Objectives: The main aim of the present study was to determine kidney function in patients with COVID-19 admitted to Imam Khomeini Hospital, Sari, Iran. Methods: The current study was cross-sectional type and its statistical sample included 498 patients with COVID-19 hospitalized in Imam Khomeini Hospital in Sari, Iran. To conduct this study, the required information including demographic, clinical and laboratory information of the patients was received and then recorded in the researcher-made checklist. Patients were evaluated in three stages (the beginning of the study, the third day of hospitalization and the sixth day of hospitalization). Finally, the result obtained for each of the aforementioned steps was recorded. Results: The results showed that 49.6% (247 people) of the evaluated patients were women and 50.4% (251 people) were men. Based on the results, the average age of the patients was 55.2 years. Among kidney disorders, chronic kidney disease (CKD) had the highest frequency (25.9%). According to kidney disease: Improving global outcomes (KDIGO), 12.9% of patients had acute kidney injury (AKI). The presence of kidney disease and the development of AKI had significant relationship with the need for intensive care unit (ICU) (P < 0.05). The results showed that although initially there was a significant relationship between kidney disease and ICU transfer (P < 0.05), but after removing the effect of age and gender variables, this relationship was not significant (P > 0.05). Conclusions: Based on the results of the present study, it can be concluded that underlying diseases such as kidney failure can be very effective in contracting COVID as well as increasing its severity, so it is necessary to take preventive measures and take special care of these patients.
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