分流支架治疗患者特异性腹主动脉瘤的比较研究

Ayat Nada, M. A. Hassan, M. Fakhr, M. El-Wakad
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引用次数: 0

摘要

血流转移(FD)支架的植入是为了减少动脉瘤的血流量,以防止破裂。我们采用计算流体动力学(CFD)方法检测腹主动脉瘤支架置入前后的血流参数。本研究旨在探讨和评估两种不同的血流支架对患者特异性腹主动脉模型的影响。研究比较两种支架的血流动力学特性,包括速度场、压力、时间平均壁剪应力(TAWSS)及其相关指标。仿真结果表明,Stent2可以进一步降低流量;Stent1具有较高的相对停留时间(RRT)。此外,Stent2降低TAWSS,增加振荡剪切指数(OSI)和内皮细胞动作电位(ECAP)。最后,Stent2保护动脉瘤不破裂,并为血栓形成创造合适的环境,这可能有助于动脉瘤降解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison Study of Flow Diverting Stents for the Treatment of a Patient-specific Abdominal Aortic Aneurysm
Flow diverting (FD) stents are implanted to decrease the aneurysm's blood flow for rupture prevention. We employed computational fluid dynamic (CFD) methods to examine pre- and post-stented flow parameters in abdominal aortic aneurysms. This study aims to investigate and evaluate the effect of two various flow stents on patient-specific abdominal aortic models. The hemodynamic characteristics of the two stents were studied and compared, including velocity field, pressure, time average wall shear stress (TAWSS), and its related indices. The simulation results show that Stent2 offers further flow reduction; however, Stent1 has a higher relative residence time (RRT). In addition, Stent2 reduces TAWSS and increases oscillatory shear index (OSI) and endothelial cell action potential (ECAP). Finally, Stent2 protects the aneurysm from rupture and creates a suitable environment for thrombus formation, which may help the aneurysm degrade.
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