铜和微量营养素对人类COVID-19影响的理论

C. A. C. D. PGDip AMP EHP-C, C. A. C. D. PGDip AMP EHP-C
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摘要

铜(Cu)通过几种不同的途径对免疫系统的功能产生强烈的影响。这些影响包括帮助单核细胞、中性粒细胞和巨噬细胞的功能,以及增强自然杀伤细胞的活性。铜还在抗菌特性和炎症反应中发挥作用。它对IL-2的产生和应答也很重要,IL-2是适应性免疫细胞的一个组成部分。此外,Cu在T细胞的增殖和分化中具有多种作用,并参与抗体的产生。缺铜甚至会导致“病毒毒力增加”。铜在医学上有着悠久的使用历史,并继续用于净水,包括在医院使用以预防军团病。疾病预防控制中心提前发布了2020年3月完成的一项研究的信息,该研究是关于COVID-19在不同表面上的寿命,包括它在铜上的寿命,它在铜上的寿命在4小时内完全死亡。此外,“几份报告表明,缺铜会削弱人体的免疫反应”。考虑到影响的多种途径,有人建议在建议水平内向铜含量低的人补充铜,以帮助他们对抗COVID-19。在推荐水平内补充铜也可能有助于预防COVID-19感染,或帮助铜含量不低的个体抵抗COVID-19感染。然而,剂量必须谨慎管理,因为过量的铜会导致神经退行性和神经发育性疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Theory on the Impact of Copper and Micronutrients Against COVID-19 in Humans
Copper (Cu) has a strong impact on the function of the immune system through several different pathways. These impacts include helping the function of monocytes, neutrophils, and macrophages, and enhancing Natural Killer cells’ activities. Cu also has a role in antimicrobial properties and inflammatory response. It is also important for IL-2 production and response, which is a component of adaptive immune cells. Additionally, Cu has multiple roles in both proliferation and differentiation of T cells and is involved in the production of antibodies. Cu deficiency can even lead to "increased viral virulence"1. Copper has a long history of use in medicine, and has continued to be used for purification of water, including use in hospitals to prevent legionnaires disease. The CDC pre released information on a study completed in March 2020 on the lifespan of COVID-19 on different surfaces which included its lifespan on copper, where it was completely dead within 4 hours. In addition, "Several reports demonstrated that Cu deficiency weakens the human immune response" 2. Given the multiple avenues of impact, it has been suggested that Cu supplementation, within recommended levels, be given to individuals who are low in Cu to help them fight off COVID-19. It is also possible that Cu supplementation, within recommended levels, may help prevent COVID-19 infection, or help individuals who are not low in Cu to fight off COVID-19 infection. However, dosage would have to be carefully managed, as excess levels of Cu can lead to both neurodegenerative and neurodevelopmental diseases.
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