内镜下扩张治疗小儿食管狭窄的回顾性分析:孟加拉国视角

R. Rashid
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摘要

背景和目的:儿童食管狭窄是一种由不同病因引起的食管内在狭窄,包括先天性异常、腐蚀性物质或异物摄入、食管手术后。本研究的目的是回顾性评价内镜下扩张(ED)在孟加拉国一家专门中心治疗食管狭窄儿童的结果和过程。方法:在2018年9月至2022年10月期间,孟加拉国专科医院(孟加拉国达卡)的21名儿童在第一次手术时接受了48次ED治疗,年龄在0.2至15岁之间。我们记录了患者的基本特征,ED的适应症,治疗程序和结果。结果参数为扩张频率、并发症(如果有的话)和临床成功率。临床成功的定义是至少一年不需要ED或反复扩张的间隔时间增加。结果:先天性食管闭锁和食入腐蚀性物质是导致食管狭窄最常见的原因。超过一半的研究患者需要多次急诊科治疗,其中一位患有先天性食管闭锁并术后狭窄的患者需要8次急诊科治疗。扩张主要使用萨瓦里-吉利亚球囊或控制径向膨胀球囊,球囊的尺寸在8.0 mm至30 mm之间。超过76%的研究患者临床成功,而其余患者临床失败或未完成治疗。结论:如果由熟练的胃肠病学家进行手术,ED获得了良好的临床成功。然而,反复扩张是常见的,特别是在有腐蚀引起的狭窄的患者中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retrospective analysis of endoscopic dilatation for pediatric patients with esophageal stricture: Bangladesh perspective
Background and objectives: Esophageal stricture in children is an intrinsic narrowing of the esophagus due to different etiologies, including congenital anomalies, corrosive substance or foreign body ingestion, and post-esophageal surgeries. The purpose of this study is to retrospectively evaluate the results and procedures of endoscopic dilatation (ED) performed on children with esophageal strictures in a specialized center in Bangladesh. Methods: Between September 2018 and October 2022, 21 children aged 0.2 to 15 years at the time of the first procedure who underwent 48 ED sessions were included at Bangladesh Specialized Hospital (Dhaka, Bangladesh). We documented the basic characteristics of patients, indications for ED, therapeutic procedures, and outcomes. Outcome parameters were the frequency of dilatations, complications (if any), and clinical success rates. Clinical success was defined as no necessity of ED for a minimum of one year or increasing intervals among repeated dilatations. Results: Among the studied patients, the most common causes of stricture were congenital esophageal atresia and ingestion of corrosive substances. More than half of the studied patients required multiple ED sessions, with one patient requiring eight sessions who had congenital esophageal atresia with a postsurgical stricture. Dilatation was achieved mostly using Savary-Gilliard or controlled radial expansion balloons varying in sizes between 8.0 mm to 30 mm. More than 76% of the studied patients had clinical success, while the rest had clinical failures or unfinished treatment. Conclusion: ED attained good clinical success if performed by skilled gastroenterologists. However, repeated dilatation is frequent, especially in patients with a corrosive-caused stricture.
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