基于事件相位分割的细粒度BCG特征识别阻塞性睡眠呼吸暂停

Fan Liu, Xingshe Zhou, Zhu Wang, Tianben Wang, Hongbo Ni, Jun Yang
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引用次数: 20

摘要

阻塞性睡眠呼吸暂停(OSA)被认为是最常见的与睡眠有关的呼吸障碍之一,它引起多种疾病,严重影响人们的日常生活。到目前为止,基于不同的信号(如PSG、ECG、鼻气流、肌电图等)来识别睡眠中OSA事件已经投入了大量的工作。但目前的研究或多或少还存在不足。在本文中,我们提出了一个新的框架来提高识别OSA事件的性能。特别是,我们的框架的关键思想是将每个潜在事件段(即可能包含或不包含OSA事件的数据段)划分为不同的阶段,从中进一步提取细粒度特征,以全面表征呼吸模式。具体地说,我们首先通过识别唤醒,从原始的弹道心动图(BCG)数据中自动定位潜在事件段。然后,通过自适应阈值分割算法将每个电位事件段划分为三个阶段(即呼吸暂停阶段、呼吸努力阶段和唤醒阶段)。基于这些阶段,我们进一步从不同方面提取和选择有效的特征来表征呼吸模式。最后,利用BP神经网络将这些潜在事件片段划分为OSA事件和非OSA事件。基于包含3790个OSA事件和2556个非OSA事件的真实BCG数据集的实验结果表明,我们的框架优于基线,precision, recall和AUC分别达到94.6%,93.1%和0.951。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Identifying Obstructive Sleep Apnea by Exploiting Fine-Grained BCG Features Based on Event Phase Segmentation
Obstructive sleep apnea (OSA) is regarded as one of the most common sleep-related breathing disorders, which causes various diseases and affects people's daily life severely. Up to now, massive efforts have been devoted to identifying OSA events during sleep based on different signals (e.g., PSG, ECG, nasal airflow and EMG, etc.). However, there still are more or less shortcomings in current studies. In this paper, we propose a novel framework to improve the performance of identifying OSA events. Particularly, the key idea of our framework is to divide each potential event segment (i.e., a data segment that may or may not contain an OSA event) into different phases, from which we further extract fine-grained features to characterize respiratory pattern comprehensively. Concretely, we first automatically locate potential event segments from raw ballistocardiography (BCG) data by identifying arousals. Afterwards, each potential event segment is divided into three phases (i.e., Apnea Phase, Respiratory Effort Phase and Arousal Phase) by an adaptive threshold-based division algorithm. Based on these phases, we further extract and select efficient features that can characterize respiratory pattern from different aspects. Finally, these potential event segments are classified into OSA events or non-OSA events using BP neural network. Experimental results based on a real BCG dataset that contains 3,790 OSA events and 2,556 non-OSA events show that our framework outperforms the baselines and the precision, recall and AUC reach 94.6%, 93.1%, and 0.951, respectively.
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