基于高效电化学读出ASIC和ABTS-CNT生物传感器的无线尿液检测系统与平台

2022 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits) Pub Date : 2022-06-12 DOI:10.1109/vlsitechnologyandcir46769.2022.9830325

Shuenn-Yuh Lee, Hao-Yun Lee, Ding-Siang Ciou, Zhan-Xian Liao, Peng-Wei Huang, Y. Hsieh, Yi-Chieh Wei, Chia-Yu Lin, Meng-Dar Shieh, Ju-Yi Chen

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引用次数: 1

摘要

本文提出了一种无线尿液检测系统和平台，该系统由电化学读出应用专用集成电路(ASIC)和2,2 ' -氮基-双(3-乙基苯并噻唑啉-6-磺酸)和碳纳米管(ABTS-CNT)组成的生物传感器组成，用于检测心血管疾病医疗保健系统中的尿白蛋白与肌酸酐比(UACR)。ASIC主要包括一个具有电流传感vco的连续时间δ - σ调制器(CTDSM)的恒电位器和一个基于混合电阻的数模转换器(R-DAC)，该转换器可以与我们开发的双通道网印碳电极(SPCE)集成，用于UACR检测。实验结果证明了所提出的尿液检测系统在实际尿液检测中的能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Wireless Urine Detection System and Platform with Power-Efficient Electrochemical Readout ASIC and ABTS-CNT Biosensor

This work presents a wireless urine detection system and platform which consists of an electrochemical readout application specific integrated circuit (ASIC) and a biosensor composed of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and carbon nanotube (ABTS-CNT) for the detection of urine albumin-to-creatinine ratio (UACR) on cardiovascular diseases healthcare system. The ASIC mainly includes a potentiostat with a current-sensing VCO-based continuous-time delta-sigma modulator (CTDSM) and a hybrid resistor-based digital-to-analog converter (R-DAC), which can be integrated with our developed dual-channel screen-printed carbon electrode (SPCE) for UACR detection. Experimental results have demonstrated the capability of the proposed urine detection system under practical urine tests.

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来源期刊

2022 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits)

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