Nicholas E. Karagas, A. Morgan, Rousseau, K. Venkatachalam
{"title":"概念与方法","authors":"Nicholas E. Karagas, A. Morgan, Rousseau, K. Venkatachalam","doi":"10.4337/9781789905601.00008","DOIUrl":null,"url":null,"abstract":"The mucolipin subgroup of the transient receptor potential superfamily of cation channels (TRPMLs) are evolutionarily conserved non-selective cation channels that function in endolysosomal membranes, and play key roles in the regulation of endocytosis, autophagy, and intracellular trafficking. Mammalian genomes encode three TRPML paralogs – TRPML1, TRPML2, and TRPML3 – that differ in tissue Ion and Molecule Transport in Lysosomes TRPML Subfamily","PeriodicalId":439406,"journal":{"name":"Handbook of Policy Transfer, Diffusion and Circulation","volume":"77 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CONCEPTS AND METHODS\",\"authors\":\"Nicholas E. Karagas, A. Morgan, Rousseau, K. Venkatachalam\",\"doi\":\"10.4337/9781789905601.00008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The mucolipin subgroup of the transient receptor potential superfamily of cation channels (TRPMLs) are evolutionarily conserved non-selective cation channels that function in endolysosomal membranes, and play key roles in the regulation of endocytosis, autophagy, and intracellular trafficking. Mammalian genomes encode three TRPML paralogs – TRPML1, TRPML2, and TRPML3 – that differ in tissue Ion and Molecule Transport in Lysosomes TRPML Subfamily\",\"PeriodicalId\":439406,\"journal\":{\"name\":\"Handbook of Policy Transfer, Diffusion and Circulation\",\"volume\":\"77 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Handbook of Policy Transfer, Diffusion and Circulation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4337/9781789905601.00008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Handbook of Policy Transfer, Diffusion and Circulation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4337/9781789905601.00008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The mucolipin subgroup of the transient receptor potential superfamily of cation channels (TRPMLs) are evolutionarily conserved non-selective cation channels that function in endolysosomal membranes, and play key roles in the regulation of endocytosis, autophagy, and intracellular trafficking. Mammalian genomes encode three TRPML paralogs – TRPML1, TRPML2, and TRPML3 – that differ in tissue Ion and Molecule Transport in Lysosomes TRPML Subfamily