{"title":"利用支持向量机对质膜、细胞膜和细胞器膜蛋白进行区分","authors":"Mehwish Faiz, A. Ahmed, S. Abid","doi":"10.1109/ICCIS54243.2021.9676407","DOIUrl":null,"url":null,"abstract":"Different membrane proteins are associated with the bio-membrane of distinct organelles which characterize their activities in and out of the cell based on their locale. Recognition of the cellular alcove is thus crucial and can be executed through machine learning algorithms. We implemented a Support Vector Machine(SVM) in order to reveal the type of membrane protein by taking the Mem Loci dataset. Before implementing SVM, we transformed the amino acid sequence into Pseudo amino acid composition and this yields an accuracy of 74%. For output, we have to enter the PseAAC of proteins and the screen reveal the category of membrane protein as either internal membrane protein or organelle membrane protein, or plasma membrane protein.","PeriodicalId":165673,"journal":{"name":"2021 4th International Conference on Computing & Information Sciences (ICCIS)","volume":"256 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Discriminating plasma membrane, internal membrane, and organelle membrane proteins by SVM\",\"authors\":\"Mehwish Faiz, A. Ahmed, S. Abid\",\"doi\":\"10.1109/ICCIS54243.2021.9676407\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Different membrane proteins are associated with the bio-membrane of distinct organelles which characterize their activities in and out of the cell based on their locale. Recognition of the cellular alcove is thus crucial and can be executed through machine learning algorithms. We implemented a Support Vector Machine(SVM) in order to reveal the type of membrane protein by taking the Mem Loci dataset. Before implementing SVM, we transformed the amino acid sequence into Pseudo amino acid composition and this yields an accuracy of 74%. For output, we have to enter the PseAAC of proteins and the screen reveal the category of membrane protein as either internal membrane protein or organelle membrane protein, or plasma membrane protein.\",\"PeriodicalId\":165673,\"journal\":{\"name\":\"2021 4th International Conference on Computing & Information Sciences (ICCIS)\",\"volume\":\"256 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2021 4th International Conference on Computing & Information Sciences (ICCIS)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICCIS54243.2021.9676407\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2021 4th International Conference on Computing & Information Sciences (ICCIS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICCIS54243.2021.9676407","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Discriminating plasma membrane, internal membrane, and organelle membrane proteins by SVM
Different membrane proteins are associated with the bio-membrane of distinct organelles which characterize their activities in and out of the cell based on their locale. Recognition of the cellular alcove is thus crucial and can be executed through machine learning algorithms. We implemented a Support Vector Machine(SVM) in order to reveal the type of membrane protein by taking the Mem Loci dataset. Before implementing SVM, we transformed the amino acid sequence into Pseudo amino acid composition and this yields an accuracy of 74%. For output, we have to enter the PseAAC of proteins and the screen reveal the category of membrane protein as either internal membrane protein or organelle membrane protein, or plasma membrane protein.